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Paracetamol-Tramadol — Competitive Intelligence Brief
marketed
Analgesic combination (non-opioid + opioid)
Cyclooxygenase (COX), opioid receptors (μ, δ, κ), norepinephrine transporter, serotonin transporter
Pain Management
Small molecule
Live · refreshed every 30 min
Target snapshot
Paracetamol-Tramadol (Paracetamol-Tramadol) — Astes. This combination drug reduces pain through two complementary mechanisms: paracetamol inhibits prostaglandin synthesis in the central nervous system, while tramadol blocks monoamine reuptake and activates opioid receptors.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Paracetamol-Tramadol TARGET | Paracetamol-Tramadol | Astes | marketed | Analgesic combination (non-opioid + opioid) | Cyclooxygenase (COX), opioid receptors (μ, δ, κ), norepinephrine transporter, serotonin transporter |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Analgesic combination (non-opioid + opioid) class)
- Astes · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Paracetamol-Tramadol — Competitive Intelligence Brief. https://druglandscape.com/ci/paracetamol-tramadol. Accessed 2026-05-17.
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