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Sohonos — Competitive Intelligence Brief

Sohonos (PALOVAROTENE) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Retinoid [EPC]. Area: Bone.

marketed Retinoid [EPC] Retinoic acid receptor gamma Bone Small molecule Live · refreshed every 30 min

Target snapshot

Sohonos (PALOVAROTENE) — Ipsen. Sohonos works by blocking the activity of a specific receptor that helps control bone growth.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Sohonos TARGET PALOVAROTENE Ipsen marketed Retinoid [EPC] Retinoic acid receptor gamma 2023-01-01
Adapalene Gel Adapalene Gel Bausch Health Americas, Inc. marketed Retinoid Retinoic acid receptor gamma (RAR-γ)
AKLIEF® AKLIEF® Teva Pharmaceuticals USA marketed Retinoic acid receptor alpha, Retinoic acid receptor beta, Retinoic acid receptor gamma
Topical Adapalene Gel 0.1% Topical Adapalene Gel 0.1% University of Louisville marketed Retinoid Retinoic acid receptor gamma (RARγ)
Adapalene 0,1% cream Adapalene 0,1% cream Dr.dr.Irma Bernadette, SpKK (K) phase 3 Retinoid Retinoic acid receptor gamma (RARγ)
Differin 0.3% Topical Gel Differin 0.3% Topical Gel Aleor Dermaceuticals Limited phase 3 Retinoid (third-generation) Retinoic acid receptor gamma (RARγ)
TRIFAROTENE TRIFAROTENE marketed Retinoid [EPC] 2019-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Retinoid [EPC] class)

  1. Bausch Health · 2 drugs in this class
  2. · 2 drugs in this class
  3. Chulalongkorn University · 1 drug in this class
  4. Galderma Labs Lp · 1 drug in this class
  5. Ipsen · 1 drug in this class
  6. Padagis LLC · 1 drug in this class
  7. Stiefel Labs Inc · 1 drug in this class
  8. Advanz · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Sohonos — Competitive Intelligence Brief. https://druglandscape.com/ci/palovarotene. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing