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PACx14 — Competitive Intelligence Brief

PACx14 (PACx14) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Multi-agent chemotherapy regimen. Area: Oncology.

phase 3 Multi-agent chemotherapy regimen Oncology Small molecule Live · refreshed every 30 min

Target snapshot

PACx14 (PACx14) — SWOG Cancer Research Network. PACx14 is a chemotherapy regimen combining paclitaxel, doxorubicin, and cyclophosphamide administered in a dose-dense schedule for cancer treatment.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
PACx14 TARGET PACx14 SWOG Cancer Research Network phase 3 Multi-agent chemotherapy regimen
Etoposide, Thioguanine, Cyclophosphamide, Busulfan, Melphalan Etoposide, Thioguanine, Cyclophosphamide, Busulfan, Melphalan Dutch Childhood Oncology Group phase 3 Multi-agent chemotherapy regimen; alkylating agents, antimetabolite, topoisomerase II inhibitor
Methotrexate, Cyclophosphamide, Cytarabine, Etoposide Methotrexate, Cyclophosphamide, Cytarabine, Etoposide St. Jude Children's Research Hospital phase 3 Multi-agent chemotherapy regimen
PAx5/PCMx5 PAx5/PCMx5 SWOG Cancer Research Network phase 3 Multi-agent chemotherapy regimen
Induction Cycles A4-5 Induction Cycles A4-5 Nationwide Children's Hospital phase 3 Multi-agent chemotherapy regimen
Course B1 +Vin Course B1 +Vin Children's Cancer Group, China phase 3 Multi-agent chemotherapy regimen
Cladribine, Cyclophosphamide, Cytarabine, Daunorubicin, Dexamethasone Cladribine, Cyclophosphamide, Cytarabine, Daunorubicin, Dexamethasone St. Jude Children's Research Hospital phase 3 Multi-agent chemotherapy regimen

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Multi-agent chemotherapy regimen class)

  1. St. Jude Children's Research Hospital · 3 drugs in this class
  2. Nationwide Children's Hospital · 2 drugs in this class
  3. SWOG Cancer Research Network · 2 drugs in this class
  4. Children's Cancer Group, China · 1 drug in this class
  5. Gruppo Italiano Studio Linfomi · 1 drug in this class
  6. Polish Adult Leukemia Group · 1 drug in this class

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Cite this brief

Drug Landscape (2026). PACx14 — Competitive Intelligence Brief. https://druglandscape.com/ci/pacx14. Accessed 2026-05-15.

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