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Ovarian Function Suppression + Aromatase Inhibitor — Competitive Intelligence Brief
phase 3
Combination endocrine therapy (GnRH agonist/antagonist + aromatase inhibitor)
GnRH receptor (ovarian suppression component) and aromatase enzyme (AI component)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Ovarian Function Suppression + Aromatase Inhibitor (Ovarian Function Suppression + Aromatase Inhibitor) — NRG Oncology. This combination suppresses ovarian estrogen production while blocking the conversion of androgens to estrogen, reducing total circulating estrogen in premenopausal women with hormone receptor-positive breast cancer.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Ovarian Function Suppression + Aromatase Inhibitor TARGET | Ovarian Function Suppression + Aromatase Inhibitor | NRG Oncology | phase 3 | Combination endocrine therapy (GnRH agonist/antagonist + aromatase inhibitor) | GnRH receptor (ovarian suppression component) and aromatase enzyme (AI component) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Combination endocrine therapy (GnRH agonist/antagonist + aromatase inhibitor) class)
- NRG Oncology · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Ovarian Function Suppression + Aromatase Inhibitor — Competitive Intelligence Brief. https://druglandscape.com/ci/ovarian-function-suppression-aromatase-inhibitor. Accessed 2026-05-16.
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