How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

How do I get this as a recurring report?

Subscribe to /feed/ci/osilodrostat.xml in any RSS reader (Feedly, Inoreader, NewsBlur). Every regulatory action, trial readout, or patent event lands in your feed automatically.

Last reviewed 2026-05-15 · How we verify

Isturisa — Competitive Intelligence Brief

Isturisa (OSILODROSTAT) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Cortisol Synthesis Inhibitor. Area: Respiratory.

marketed Cortisol Synthesis Inhibitor Cytochrome P450 11B2, mitochondrial Respiratory Small molecule Live · refreshed every 30 min

Target snapshot

Isturisa (OSILODROSTAT) — Recordati. Isturisa blocks the production of cortisol in the adrenal glands by inhibiting the cytochrome P450 11B2 enzyme.

Comparator set (3 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Isturisa TARGET	OSILODROSTAT	Recordati	marketed	Cortisol Synthesis Inhibitor	Cytochrome P450 11B2, mitochondrial	2020-01-01
Amidate	ETOMIDATE	Pfizer	marketed	General Anesthetic [EPC]	Cytochrome P450 11B2, mitochondrial	1982-01-01
Zytiga	Zytiga	Bukwang Pharmaceutical	marketed		Cytochrome P450 11B2, mitochondrial, Androgen receptor, Cytochrome P450 11B1, mitochondrial
Recorlev	LEVOKETOCONAZOLE	Strongbridge	marketed	Cortisol Synthesis Inhibitor [EPC]		2021-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Cortisol Synthesis Inhibitor class)

Recordati · 1 drug in this class

Subscribe to ongoing alerts

Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:

Cite this brief

Drug Landscape (2026). Isturisa — Competitive Intelligence Brief. https://druglandscape.com/ci/osilodrostat. Accessed 2026-05-15.

Build your own brief

Pick any drug + add comparators:

https://druglandscape.com/ci/{slug} — auto-detected competitors
https://druglandscape.com/ci/{slug}?vs=drug1,drug2,drug3 — explicit comparators
Brand names auto-resolve: /ci/keytruda → 301 → /ci/pembrolizumab