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Optimised dose rifampicin — Competitive Intelligence Brief
phase 3
Antibiotic (rifamycin)
Bacterial RNA polymerase
Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
Optimised dose rifampicin (Optimised dose rifampicin) — Radboud University Medical Center. Optimised dose rifampicin inhibits bacterial RNA polymerase to suppress mycobacterial protein synthesis and growth.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Optimised dose rifampicin TARGET | Optimised dose rifampicin | Radboud University Medical Center | phase 3 | Antibiotic (rifamycin) | Bacterial RNA polymerase | |
| Rifampicin (R) | Rifampicin (R) | University College, London | marketed | Rifamycin antibiotic | Bacterial RNA polymerase β-subunit | |
| Rifamycin-containing regimen | Rifamycin-containing regimen | National Taiwan University Hospital | marketed | Rifamycin antibiotic | Bacterial RNA polymerase | |
| Rifampin/isoniazid FDC | Rifampin/isoniazid FDC | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | marketed | Antituberculous agent (fixed-dose combination) | Bacterial RNA polymerase (rifampin); mycolic acid biosynthesis (isoniazid) | |
| HR | HR | Global Alliance for TB Drug Development | marketed | Anti-tuberculosis agent (fixed-dose combination) | Mycobacterial cell wall (isoniazid) and bacterial RNA polymerase (rifampicin) | |
| amoxicillin rifabutin | amoxicillin rifabutin | Shanghai Jiao Tong University School of Medicine | marketed | Combination antibiotic (beta-lactam + rifamycin) | Penicillin-binding proteins (amoxicillin); bacterial RNA polymerase (rifabutin) | |
| Rifampin (RIF) | Rifampin (RIF) | National Institute of Allergy and Infectious Diseases (NIAID) | marketed | Rifamycin antibiotic | Bacterial RNA polymerase (RNAP) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antibiotic (rifamycin) class)
- Radboud University Medical Center · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Optimised dose rifampicin — Competitive Intelligence Brief. https://druglandscape.com/ci/optimised-dose-rifampicin. Accessed 2026-06-10.
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