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Once-daily ABC+3TC — Competitive Intelligence Brief
marketed
Nucleoside reverse transcriptase inhibitor (NRTI) combination
HIV reverse transcriptase
Infectious Disease / Virology
Small molecule
Live · refreshed every 30 min
Target snapshot
Once-daily ABC+3TC (Once-daily ABC+3TC) — Medical Research Council. ABC+3TC is a fixed-dose combination of two nucleoside reverse transcriptase inhibitors (NRTIs) that blocks HIV reverse transcriptase to prevent viral replication.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Once-daily ABC+3TC TARGET | Once-daily ABC+3TC | Medical Research Council | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) combination | HIV reverse transcriptase | |
| Reyataz + Epzicom | Reyataz + Epzicom | ViiV Healthcare | marketed | Antiretroviral combination (protease inhibitor + nucleoside reverse transcriptase inhibitors) | HIV protease; HIV reverse transcriptase | |
| TDF/3TC/EFV | TDF/3TC/EFV | Peking Union Medical College Hospital | marketed | Antiretroviral combination therapy (NRTI + NNRTI) | HIV reverse transcriptase | |
| Lamiduvine (Epivir) | Lamiduvine (Epivir) | Catholic University of the Sacred Heart | marketed | Nucleoside Reverse Transcriptase Inhibitor (NRTI) | HIV reverse transcriptase | |
| Doravirine + tenofovir DF + lamivudine | Doravirine + tenofovir DF + lamivudine | Instituto Mexicano del Seguro Social | marketed | Antiretroviral combination (NNRTI + NRTIs) | HIV reverse transcriptase | |
| Abacavir/lamivudine/zidovudine | Abacavir/lamivudine/zidovudine | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) combination | HIV reverse transcriptase | |
| Zidovudine (drug) | Zidovudine (drug) | Johann Wolfgang Goethe University Hospital | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) | HIV reverse transcriptase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Nucleoside reverse transcriptase inhibitor (NRTI) combination class)
- Medical Research Council · 2 drugs in this class
- Bristol-Myers Squibb · 1 drug in this class
- Fundacion SEIMC-GESIDA · 1 drug in this class
- GlaxoSmithKline · 1 drug in this class
- Janssen Scientific Affairs, LLC · 1 drug in this class
- Merck Sharp & Dohme LLC · 1 drug in this class
- National Institute of Allergy and Infectious Diseases (NIAID) · 1 drug in this class
- Tibotec, Inc · 1 drug in this class
- University of North Carolina, Chapel Hill · 1 drug in this class
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Once-daily ABC+3TC — Competitive Intelligence Brief. https://druglandscape.com/ci/once-daily-abc-3tc. Accessed 2026-05-16.
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