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olanzapine therapy — Competitive Intelligence Brief
marketed
Atypical antipsychotic
Dopamine D2 receptor; Serotonin 5-HT2A receptor
Psychiatry
Small molecule
Live · refreshed every 30 min
Target snapshot
olanzapine therapy (olanzapine therapy) — Eli Lilly and Company. Olanzapine is an atypical antipsychotic that blocks dopamine D2 and serotonin 5-HT2A receptors in the brain to reduce psychotic symptoms and stabilize mood.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| olanzapine therapy TARGET | olanzapine therapy | Eli Lilly and Company | marketed | Atypical antipsychotic | Dopamine D2 receptor; Serotonin 5-HT2A receptor | |
| Risperidone high dose | Risperidone high dose | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | marketed | Atypical antipsychotic | Dopamine D2 receptor; Serotonin 5-HT2A receptor | |
| ziprasidone or olanzapine | ziprasidone or olanzapine | Medical University of Vienna | marketed | Atypical antipsychotic | Dopamine D2 receptor; Serotonin 5-HT2A receptor | |
| Perospirone hydrochloride tablets | Perospirone hydrochloride tablets | Shanghai Mental Health Center | marketed | Atypical antipsychotic | Dopamine D2 receptor; Serotonin 5-HT2A receptor | |
| Aripiprazole; Quetiapine | Aripiprazole; Quetiapine | Taichung Veterans General Hospital | marketed | Atypical antipsychotic combination | Dopamine D2 receptor; Serotonin 5-HT2A receptor; Serotonin 5-HT1A receptor | |
| Risperidone tablets | Risperidone tablets | Sumitomo Pharma (Suzhou) Co., Ltd. | marketed | Atypical antipsychotic | Dopamine D2 receptor; Serotonin 5-HT2A receptor | |
| Intramuscular olanzapine, aripiprazole | Intramuscular olanzapine, aripiprazole | Veterans Medical Research Foundation | marketed | Atypical antipsychotic | Dopamine D2 receptor; serotonin 5-HT2A receptor (olanzapine); dopamine D2 partial agonist (aripiprazole) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Atypical antipsychotic class)
- Shanghai Mental Health Center · 10 drugs in this class
- AstraZeneca · 6 drugs in this class
- Otsuka Pharmaceutical Development & Commercialization, Inc. · 5 drugs in this class
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · 4 drugs in this class
- Eli Lilly and Company · 4 drugs in this class
- Otsuka Pharmaceutical Co., Ltd. · 3 drugs in this class
- Medical University of Vienna · 2 drugs in this class
- Organon and Co · 2 drugs in this class
- Chengdu Kanghong Pharmaceutical Group Co., Ltd. · 2 drugs in this class
- H. Lundbeck A/S · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). olanzapine therapy — Competitive Intelligence Brief. https://druglandscape.com/ci/olanzapine-therapy. Accessed 2026-06-10.
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