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NVP+AZT — Competitive Intelligence Brief
phase 3
Antiretroviral combination therapy (NNRTI + NRTI)
HIV reverse transcriptase
Infectious Disease / Virology
Small molecule
Live · refreshed every 30 min
Target snapshot
NVP+AZT (NVP+AZT) — Johns Hopkins Bloomberg School of Public Health. NVP+AZT is a combination antiretroviral therapy that inhibits HIV reverse transcriptase through two nucleoside reverse transcriptase inhibitors (NRTIs), preventing viral replication.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| NVP+AZT TARGET | NVP+AZT | Johns Hopkins Bloomberg School of Public Health | phase 3 | Antiretroviral combination therapy (NNRTI + NRTI) | HIV reverse transcriptase | |
| EFV | EFV | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | marketed | Non-nucleoside reverse transcriptase inhibitor (NNRTI) | HIV reverse transcriptase | |
| Tenofovir/Emtricitabine | Tenofovir/Emtricitabine | Bristol-Myers Squibb | marketed | Nucleoside/nucleotide reverse transcriptase inhibitor (NRTI/NtRTI) combination | HIV reverse transcriptase | |
| AZT | AZT | Johns Hopkins Bloomberg School of Public Health | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) | HIV reverse transcriptase | |
| Tenofovir (TDF) | Tenofovir (TDF) | French National Agency for Research on AIDS and Viral Hepatitis | marketed | Nucleotide reverse transcriptase inhibitor (NtRTI) | HIV reverse transcriptase; Hepatitis B polymerase | |
| Twice-daily ABC+3TC | Twice-daily ABC+3TC | Medical Research Council | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) combination | HIV reverse transcriptase | |
| LPV/r + TDF/FTC or TDF/3TC | LPV/r + TDF/FTC or TDF/3TC | The HIV Netherlands Australia Thailand Research Collaboration | marketed | Antiretroviral combination therapy (protease inhibitor + nucleoside reverse transcriptase inhibitors) | HIV protease; HIV reverse transcriptase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antiretroviral combination therapy (NNRTI + NRTI) class)
- Johns Hopkins Bloomberg School of Public Health · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). NVP+AZT — Competitive Intelligence Brief. https://druglandscape.com/ci/nvp-azt. Accessed 2026-05-17.
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