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NP101 - Sumatriptan iontophoretic transdermal patch — Competitive Intelligence Brief

NP101 - Sumatriptan iontophoretic transdermal patch (NP101 - Sumatriptan iontophoretic transdermal patch) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: 5-HT1B/1D receptor agonist (triptan). Area: Neurology.

phase 3 5-HT1B/1D receptor agonist (triptan) 5-HT1B receptor, 5-HT1D receptor Neurology Small molecule Live · refreshed every 30 min

Target snapshot

NP101 - Sumatriptan iontophoretic transdermal patch (NP101 - Sumatriptan iontophoretic transdermal patch) — NuPathe Inc.. NP101 delivers sumatriptan through the skin via iontophoresis, a technique using electrical current to enhance transdermal penetration, allowing rapid absorption without needles or oral administration.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
NP101 - Sumatriptan iontophoretic transdermal patch TARGET NP101 - Sumatriptan iontophoretic transdermal patch NuPathe Inc. phase 3 5-HT1B/1D receptor agonist (triptan) 5-HT1B receptor, 5-HT1D receptor
naratriptan HCl naratriptan HCl Cady, Roger, M.D. marketed Triptan (5-HT1B/1D receptor agonist) 5-HT1B receptor, 5-HT1D receptor
Sumatriptan Succinate Oral Tablet Sumatriptan Succinate Oral Tablet Damanhour Teaching Hospital marketed Triptan (5-HT1B/1D receptor agonist) 5-HT1B receptor, 5-HT1D receptor
sumatriptan succinate/naproxen sodium sumatriptan succinate/naproxen sodium GlaxoSmithKline marketed 5-HT1B/1D receptor agonist combined with NSAID 5-HT1B receptor, 5-HT1D receptor, COX-1, COX-2
Migranal nasal spray at 4 hour Migranal nasal spray at 4 hour Thomas Jefferson University marketed Ergot alkaloid; 5-HT1B/1D receptor agonist 5-HT1B receptor, 5-HT1D receptor
Migranal nasal spray at 1 hour Migranal nasal spray at 1 hour Thomas Jefferson University marketed Ergot alkaloid; serotonin receptor agonist 5-HT1B receptor, 5-HT1D receptor
Comparator: Rizatriptan Comparator: Rizatriptan Organon and Co phase 3 Triptan (5-HT1B/1D receptor agonist) 5-HT1B receptor, 5-HT1D receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (5-HT1B/1D receptor agonist (triptan) class)

  1. NuPathe Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). NP101 - Sumatriptan iontophoretic transdermal patch — Competitive Intelligence Brief. https://druglandscape.com/ci/np101-sumatriptan-iontophoretic-transdermal-patch. Accessed 2026-06-09.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing