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NP101 - Sumatriptan iontophoretic transdermal patch — Competitive Intelligence Brief
Target snapshot
NP101 - Sumatriptan iontophoretic transdermal patch (NP101 - Sumatriptan iontophoretic transdermal patch) — NuPathe Inc.. NP101 delivers sumatriptan through the skin via iontophoresis, a technique using electrical current to enhance transdermal penetration, allowing rapid absorption without needles or oral administration.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| NP101 - Sumatriptan iontophoretic transdermal patch TARGET | NP101 - Sumatriptan iontophoretic transdermal patch | NuPathe Inc. | phase 3 | 5-HT1B/1D receptor agonist (triptan) | 5-HT1B receptor, 5-HT1D receptor | |
| naratriptan HCl | naratriptan HCl | Cady, Roger, M.D. | marketed | Triptan (5-HT1B/1D receptor agonist) | 5-HT1B receptor, 5-HT1D receptor | |
| Sumatriptan Succinate Oral Tablet | Sumatriptan Succinate Oral Tablet | Damanhour Teaching Hospital | marketed | Triptan (5-HT1B/1D receptor agonist) | 5-HT1B receptor, 5-HT1D receptor | |
| sumatriptan succinate/naproxen sodium | sumatriptan succinate/naproxen sodium | GlaxoSmithKline | marketed | 5-HT1B/1D receptor agonist combined with NSAID | 5-HT1B receptor, 5-HT1D receptor, COX-1, COX-2 | |
| Migranal nasal spray at 4 hour | Migranal nasal spray at 4 hour | Thomas Jefferson University | marketed | Ergot alkaloid; 5-HT1B/1D receptor agonist | 5-HT1B receptor, 5-HT1D receptor | |
| Migranal nasal spray at 1 hour | Migranal nasal spray at 1 hour | Thomas Jefferson University | marketed | Ergot alkaloid; serotonin receptor agonist | 5-HT1B receptor, 5-HT1D receptor | |
| Comparator: Rizatriptan | Comparator: Rizatriptan | Organon and Co | phase 3 | Triptan (5-HT1B/1D receptor agonist) | 5-HT1B receptor, 5-HT1D receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (5-HT1B/1D receptor agonist (triptan) class)
- NuPathe Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). NP101 - Sumatriptan iontophoretic transdermal patch — Competitive Intelligence Brief. https://druglandscape.com/ci/np101-sumatriptan-iontophoretic-transdermal-patch. Accessed 2026-06-09.
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