Who are neostigmine and glycopyrrolate or atropine's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Neostigmine w/ Glycopyrrolate, Neostigmine + Glycopyrrolate, neostigmine/glycopyrolate, Neostigmine with glycopyrrolate, Neostigmine and Glycopyrrolate, Combination of Neostigmine and Glycopyrrolate.

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Last reviewed 2026-05-17 · How we verify

neostigmine and glycopyrrolate or atropine — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

neostigmine and glycopyrrolate or atropine (neostigmine and glycopyrrolate or atropine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Cholinesterase inhibitor with anticholinergic agent. Area: Neuromuscular disorders.

phase 3 Cholinesterase inhibitor with anticholinergic agent Acetylcholinesterase (neostigmine); muscarinic acetylcholine receptors (glycopyrrolate/atropine) Neuromuscular disorders Small molecule Live · refreshed every 30 min

Target snapshot

neostigmine and glycopyrrolate or atropine (neostigmine and glycopyrrolate or atropine) — Merck Sharp & Dohme LLC. Neostigmine inhibits acetylcholinesterase to increase acetylcholine levels, while glycopyrrolate or atropine blocks muscarinic receptors to prevent cholinergic side effects.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
neostigmine and glycopyrrolate or atropine TARGET	neostigmine and glycopyrrolate or atropine	Merck Sharp & Dohme LLC	phase 3	Cholinesterase inhibitor with anticholinergic agent	Acetylcholinesterase (neostigmine); muscarinic acetylcholine receptors (glycopyrrolate/atropine)
Neostigmine w/ Glycopyrrolate	Neostigmine w/ Glycopyrrolate	University of Texas Southwestern Medical Center	marketed	Acetylcholinesterase inhibitor with anticholinergic agent	Acetylcholinesterase (neostigmine); muscarinic acetylcholine receptors (glycopyrrolate)
Neostigmine + Glycopyrrolate	Neostigmine + Glycopyrrolate	Merck Sharp & Dohme LLC	marketed	Acetylcholinesterase inhibitor with anticholinergic agent	Acetylcholinesterase (neostigmine); Muscarinic acetylcholine receptors (glycopyrrolate)
neostigmine/glycopyrolate	neostigmine/glycopyrolate	Henry Ford Health System	marketed	Cholinesterase inhibitor with anticholinergic agent	Acetylcholinesterase (neostigmine); muscarinic acetylcholine receptors (glycopyrolate)
Neostigmine with glycopyrrolate	Neostigmine with glycopyrrolate	The Cleveland Clinic	marketed	Acetylcholinesterase inhibitor with anticholinergic agent	Acetylcholinesterase; muscarinic acetylcholine receptors
Neostigmine and Glycopyrrolate	Neostigmine and Glycopyrrolate	James J. Peters Veterans Affairs Medical Center	marketed	Cholinesterase inhibitor with anticholinergic agent	Acetylcholinesterase (neostigmine); Muscarinic acetylcholine receptors (glycopyrrolate)
Combination of Neostigmine and Glycopyrrolate	Combination of Neostigmine and Glycopyrrolate	James J. Peters Veterans Affairs Medical Center	phase 3	Cholinesterase inhibitor with anticholinergic agent	Acetylcholinesterase (neostigmine); Muscarinic acetylcholine receptors (glycopyrrolate)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Cholinesterase inhibitor with anticholinergic agent class)

James J. Peters Veterans Affairs Medical Center · 2 drugs in this class
Henry Ford Health System · 1 drug in this class
Merck Sharp & Dohme LLC · 1 drug in this class

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Cite this brief

Drug Landscape (2026). neostigmine and glycopyrrolate or atropine — Competitive Intelligence Brief. https://druglandscape.com/ci/neostigmine-and-glycopyrrolate-or-atropine. Accessed 2026-05-17.

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