Mucopolysaccharide Polysulfate Cream and glucocorticoids — Competitive Intelligence Brief

Mucopolysaccharide Polysulfate Cream and glucocorticoids (Mucopolysaccharide Polysulfate Cream and glucocorticoids) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Glucocorticoid. Area: Dermatology, Immunology, Gastroenterology.

phase 2 Glucocorticoid Glucocorticoid receptor (GR) Dermatology, Immunology, Gastroenterology Small molecule

Target snapshot

Mucopolysaccharide Polysulfate Cream and glucocorticoids (Mucopolysaccharide Polysulfate Cream and glucocorticoids) — Shenzhen Kangzhe Pharmaceutical Co., Ltd.. Glucocorticoids exert their effects by binding to the glucocorticoid receptor (GR) in the cytoplasm, which then translocates to the nucleus and regulates gene expression.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Mucopolysaccharide Polysulfate Cream and glucocorticoids TARGET	Mucopolysaccharide Polysulfate Cream and glucocorticoids	Shenzhen Kangzhe Pharmaceutical Co., Ltd.	phase 2	Glucocorticoid	Glucocorticoid receptor (GR)
Medrol	methylprednisolone	Generic (originally Upjohn/Pfizer)	marketed	Glucocorticoid (corticosteroid)	Annexin A1, Short transient receptor potential channel 5, Glucocorticoid receptor	1957-10-01
Prelone	prednisolone	Generic (originally Schering)	marketed	Glucocorticoid (corticosteroid)	Annexin A1, Corticosteroid-binding globulin, G-protein coupled bile acid receptor 1	1955-01-01
Hydrocortisone/ Placebo and Propranolol	Hydrocortisone/ Placebo and Propranolol	University of Dundee	marketed	Glucocorticoid + Beta-blocker combination	Glucocorticoid receptor; Beta-1 and Beta-2 adrenergic receptors
Methylprednisolone (drug)	Methylprednisolone (drug)	University Hospital, Bordeaux	marketed	Glucocorticoid (corticosteroid)	Glucocorticoid receptor (GR)
Conventional 24-week glucocorticoid regimen	Conventional 24-week glucocorticoid regimen	First Affiliated Hospital of Wenzhou Medical University	marketed	Glucocorticoid	Glucocorticoid receptor (GR)
Prednisone/Prednisolone/Methylprednisolone	Prednisone/Prednisolone/Methylprednisolone	Hoffmann-La Roche	marketed	Corticosteroid (glucocorticoid)	Glucocorticoid receptor (GR)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Glucocorticoid class)

1. Research in Real-Life Ltd · 2 drugs in this class
2. NICHD Neonatal Research Network · 2 drugs in this class
3. UMC Utrecht · 2 drugs in this class
4. University of Pennsylvania · 2 drugs in this class
5. First Affiliated Hospital of Zhejiang University · 1 drug in this class
6. GlaxoSmithKline · 1 drug in this class
7. ClinAmygate · 1 drug in this class
8. Instituto de Investigación Sanitaria y Biomédica de Alicante · 1 drug in this class
9. First Affiliated Hospital of Wenzhou Medical University · 1 drug in this class
10. Guangzhou JOYO Pharma Co., Ltd · 1 drug in this class