Last reviewed · How we verify
Mizoribine (MZR) — Competitive Intelligence Brief
phase 3
IMPDH inhibitor; immunosuppressant
IMPDH (inosine monophosphate dehydrogenase)
Immunology; Transplantation
Small molecule
Live · refreshed every 30 min
Target snapshot
Mizoribine (MZR) (Mizoribine (MZR)) — Asahi Kasei Pharma Corporation. Mizoribine inhibits inosine monophosphate dehydrogenase (IMPDH) to suppress guanine nucleotide synthesis and reduce T and B cell proliferation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Mizoribine (MZR) TARGET | Mizoribine (MZR) | Asahi Kasei Pharma Corporation | phase 3 | IMPDH inhibitor; immunosuppressant | IMPDH (inosine monophosphate dehydrogenase) | |
| sirolimus (drug), mmf (drug) | sirolimus (drug), mmf (drug) | University Hospital Muenster | marketed | Immunosuppressive agents (mTOR inhibitor + IMPDH inhibitor combination) | mTOR (sirolimus); IMPDH type II (MMF) | |
| Mycophenylate mofetil | Mycophenylate mofetil | Masonic Cancer Center, University of Minnesota | marketed | Immunosuppressant, IMPDH inhibitor | Inosine monophosphate dehydrogenase (IMPDH) type II | |
| Mycophenolate mofetil Tab./Cap. | Mycophenolate mofetil Tab./Cap. | Chong Kun Dang Pharmaceutical | marketed | Immunosuppressant; IMPDH inhibitor | Inosine monophosphate dehydrogenase (IMPDH) type II | |
| Mycophenolic Acid (MPA) | Mycophenolic Acid (MPA) | Novartis | marketed | Immunosuppressant; IMPDH inhibitor | Inosine monophosphate dehydrogenase (IMPDH) type II | |
| Placebo to Mycophenolate mofetil | Placebo to Mycophenolate mofetil | Hoffmann-La Roche | marketed | Immunosuppressant; IMPDH inhibitor | Inosine monophosphate dehydrogenase (IMPDH) type II | |
| Mycophenolic Acid Oral Product | Mycophenolic Acid Oral Product | Simon Tremblay, PharmD, PhD | marketed | Immunosuppressant; IMPDH inhibitor | Inosine monophosphate dehydrogenase (IMPDH) type II |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (IMPDH inhibitor; immunosuppressant class)
- Asahi Kasei Pharma Corporation · 1 drug in this class
Subscribe to ongoing alerts
Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:
- Mizoribine (MZR) CI watch — RSS
- Mizoribine (MZR) CI watch — Atom
- Mizoribine (MZR) CI watch — JSON
- Mizoribine (MZR) alone — RSS
- Whole IMPDH inhibitor; immunosuppressant class — RSS
Cite this brief
Drug Landscape (2026). Mizoribine (MZR) — Competitive Intelligence Brief. https://druglandscape.com/ci/mizoribine-mzr. Accessed 2026-05-17.
Build your own brief
Pick any drug + add comparators:
https://druglandscape.com/ci/{slug}— auto-detected competitorshttps://druglandscape.com/ci/{slug}?vs=drug1,drug2,drug3— explicit comparators- Brand names auto-resolve:
/ci/keytruda→ 301 →/ci/pembrolizumab