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Medrol — Competitive Intelligence Brief
marketed
Glucocorticoid (corticosteroid)
Annexin A1, Short transient receptor potential channel 5, Glucocorticoid receptor
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Medrol (methylprednisolone) — Generic (originally Upjohn/Pfizer). Potent synthetic glucocorticoid with 5x hydrocortisone potency and minimal mineralocorticoid activity, used for severe inflammatory conditions.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Medrol TARGET | methylprednisolone | Generic (originally Upjohn/Pfizer) | marketed | Glucocorticoid (corticosteroid) | Annexin A1, Short transient receptor potential channel 5, Glucocorticoid receptor | 1957-10-01 |
| Methylprednisolon | Methylprednisolon | Leiden University Medical Center | marketed | Annexin A1, Short transient receptor potential channel 5, Glucocorticoid receptor | ||
| Prelone | prednisolone | Generic (originally Schering) | marketed | Glucocorticoid (corticosteroid) | Annexin A1, Corticosteroid-binding globulin, G-protein coupled bile acid receptor 1 | 1955-01-01 |
| Dexamethasone physician choice | Dexamethasone physician choice | Ottawa Hospital Research Institute | marketed | Glucocorticoid (corticosteroid) | Glucocorticoid receptor (GR) | |
| IV dexamethasone | IV dexamethasone | University Health Network, Toronto | marketed | Glucocorticoid (corticosteroid) | Glucocorticoid receptor (GR) | |
| Dexamethasone low dose | Dexamethasone low dose | Manuel Taboada Muñiz | marketed | Glucocorticoid (corticosteroid) | Glucocorticoid receptor (GR) | |
| Dexamethasone (IV) | Dexamethasone (IV) | Cancer Trials Ireland | marketed | Glucocorticoid (corticosteroid) | Glucocorticoid receptor (GR) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Glucocorticoid (corticosteroid) class)
- Merck Sharp & Dohme LLC · 2 drugs in this class
- The Children's Hospital of Zhejiang University School of Medicine · 2 drugs in this class
- Vanderbilt University Medical Center · 2 drugs in this class
- Fujian Shengdi Pharmaceutical Co., Ltd. · 1 drug in this class
- Hamad Medical Corporation · 1 drug in this class
- Hoffmann-La Roche · 1 drug in this class
- Generic (originally Upjohn/Pfizer) · 1 drug in this class
- Manuel Taboada Muñiz · 1 drug in this class
- Masonic Cancer Center, University of Minnesota · 1 drug in this class
- Hospital for Special Surgery, New York · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Medrol — Competitive Intelligence Brief. https://druglandscape.com/ci/methylprednisolone. Accessed 2026-05-13.
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