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Metformin Small Pack — Competitive Intelligence Brief

Metformin Small Pack (Metformin Small Pack) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Biguanide. Area: Diabetes.

marketed Biguanide AMP-activated protein kinase (AMPK); complex I of the mitochondrial electron transport chain Diabetes Small molecule Live · refreshed every 30 min

Target snapshot

Metformin Small Pack (Metformin Small Pack) — GlaxoSmithKline. Metformin reduces hepatic glucose production and improves insulin sensitivity in peripheral tissues, lowering blood glucose levels in type 2 diabetes.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Metformin Small Pack TARGET Metformin Small Pack GlaxoSmithKline marketed Biguanide AMP-activated protein kinase (AMPK); complex I of the mitochondrial electron transport chain
Metformin / alogliptin Oral Product Metformin / alogliptin Oral Product University of Catanzaro marketed Biguanide / DPP-4 inhibitor combination Metformin: mitochondrial glycerophosphate dehydrogenase; Alogliptin: dipeptidyl peptidase-4 (DPP-4)
Detemir insulin, Aspart insulin, Metformin Detemir insulin, Aspart insulin, Metformin University Hospital, Toulouse marketed Insulin combination with biguanide Insulin receptor (detemir and aspart); AMPK and mitochondrial glycerophosphate dehydrogenase (metformin)
MET + Glibenclamide Group MET + Glibenclamide Group Hospital de Clinicas de Porto Alegre marketed Antidiabetic combination (biguanide + sulfonylurea) AMPK pathway (metformin); ATP-sensitive potassium channel (glibenclamide)
Met IR Met IR Elcelyx Therapeutics, Inc. marketed Biguanide AMP-activated protein kinase (AMPK)
metformin + glimepiride metformin + glimepiride GlaxoSmithKline marketed Antidiabetic combination (biguanide + sulfonylurea) Metformin: mitochondrial glycerophosphate dehydrogenase; Glimepiride: ATP-sensitive potassium channel (KATP)
Mandated back ground therapy Mandated back ground therapy Sanofi marketed biguanide

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Biguanide class)

  1. AstraZeneca · 4 drugs in this class
  2. Merck Sharp & Dohme LLC · 3 drugs in this class
  3. University of Texas Southwestern Medical Center · 2 drugs in this class
  4. Mount Sinai Hospital, Canada · 2 drugs in this class
  5. GlaxoSmithKline · 2 drugs in this class
  6. Eli Lilly and Company · 2 drugs in this class
  7. University Magna Graecia · 2 drugs in this class
  8. First Affiliated Hospital of Wenzhou Medical University · 1 drug in this class
  9. Ente Ospedaliero Ospedali Galliera · 1 drug in this class
  10. Daewoong Pharmaceutical Co. LTD. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Metformin Small Pack — Competitive Intelligence Brief. https://druglandscape.com/ci/metformin-small-pack. Accessed 2026-05-13.

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