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mercaptopurine tablet — Competitive Intelligence Brief

mercaptopurine tablet (mercaptopurine tablet) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Purine analog antimetabolite. Area: Oncology.

phase 3 Purine analog antimetabolite Hypoxanthine-guanine phosphoribosyltransferase (HGPRT), thiopurine methyltransferase (TPMT), and purine synthesis pathway enzymes Oncology Small molecule Live · refreshed every 30 min

Target snapshot

mercaptopurine tablet (mercaptopurine tablet) — National Cancer Institute (NCI). Mercaptopurine is a purine analog that inhibits nucleotide synthesis and DNA replication, leading to cell death in rapidly dividing cells.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
mercaptopurine tablet TARGET mercaptopurine tablet National Cancer Institute (NCI) phase 3 Purine analog antimetabolite Hypoxanthine-guanine phosphoribosyltransferase (HGPRT), thiopurine methyltransferase (TPMT), and purine synthesis pathway enzymes
Fludarabine (Flud) Fludarabine (Flud) Technische Universität Dresden marketed Purine analog antimetabolite Ribonucleotide reductase, DNA polymerase
6MP 6MP South China Children's Leukemia Group marketed Purine analog antimetabolite Hypoxanthine-guanine phosphoribosyltransferase (HGPRT), inosine monophosphate dehydrogenase (IMPDH)
Fludarabine (Bayer) Fludarabine (Bayer) Chinese PLA General Hospital marketed Purine analog antimetabolite Ribonucleotide reductase, DNA polymerase
Mercaptopurine, Imatinib Mercaptopurine, Imatinib St. Jude Children's Research Hospital phase 3 Purine analog antimetabolite and tyrosine kinase inhibitor combination Purine metabolism enzymes (mercaptopurine); BCR-ABL, c-KIT, PDGFR (imatinib)
Fludarabine mono Fludarabine mono German CLL Study Group phase 3 Purine analog antimetabolite Ribonucleotide reductase; DNA polymerase
Experimental (fludarabine) Experimental (fludarabine) French Innovative Leukemia Organisation phase 3 Purine analog antimetabolite Ribonucleotide reductase, DNA polymerase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Purine analog antimetabolite class)

  1. Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · 1 drug in this class
  2. Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · 1 drug in this class
  3. Chinese PLA General Hospital · 1 drug in this class
  4. French Innovative Leukemia Organisation · 1 drug in this class
  5. German CLL Study Group · 1 drug in this class
  6. National Cancer Institute (NCI) · 1 drug in this class
  7. South China Children's Leukemia Group · 1 drug in this class
  8. Technische Universität Dresden · 1 drug in this class
  9. University of California, San Francisco · 1 drug in this class

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Cite this brief

Drug Landscape (2026). mercaptopurine tablet — Competitive Intelligence Brief. https://druglandscape.com/ci/mercaptopurine-tablet. Accessed 2026-05-17.

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