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Nucala — Competitive Intelligence Brief

Nucala (MEPOLIZUMAB) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Interleukin-5 Antagonist [EPC]. Area: Respiratory.

marketed Interleukin-5 Antagonist [EPC] Interleukin-5 Respiratory Monoclonal antibody Live · refreshed every 30 min

Target snapshot

Nucala (MEPOLIZUMAB) — GSK. Nucala works by binding to interleukin-5, a protein that stimulates the production of eosinophils.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Nucala TARGET MEPOLIZUMAB GSK marketed Interleukin-5 Antagonist [EPC] Interleukin-5 2015-01-01
Fasenra BENRALIZUMAB AstraZeneca marketed Interleukin-5 Receptor alpha-directed Cytolytic Antibody [EPC] Interleukin-5 receptor subunit alpha 2017-01-01
Cinqair RESLIZUMAB Teva Respiratory Llc marketed Interleukin-5 Antagonist [EPC] Interleukin-5 2016-01-01
Nucala Nucala Mayo Clinic marketed Interleukin-5
Fasenra® Fasenra® AstraZeneca marketed IL-5 receptor antagonist monoclonal antibody IL-5Rα (interleukin-5 receptor alpha)
Mepolizumab Injection [Nucala] Mepolizumab Injection [Nucala] KU Leuven marketed IL-5 antagonist monoclonal antibody IL-5 (Interleukin-5)
Mepolizumab 100 milligrams Mepolizumab 100 milligrams GlaxoSmithKline phase 3 IL-5 antagonist monoclonal antibody IL-5 (Interleukin-5)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Interleukin-5 Antagonist [EPC] class)

  1. GSK · 1 drug in this class
  2. Teva Respiratory Llc · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Nucala — Competitive Intelligence Brief. https://druglandscape.com/ci/mepolizumab. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing