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Memantine (Ebixa) — Competitive Intelligence Brief
phase 3
NMDA receptor antagonist
NMDA receptor
Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
Memantine (Ebixa) (Memantine (Ebixa)) — University of Lisbon. Memantine is an uncompetitive antagonist of the N-methyl-D-aspartate (NMDA) receptor that blocks excessive glutamate signaling in the brain.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Memantine (Ebixa) TARGET | Memantine (Ebixa) | University of Lisbon | phase 3 | NMDA receptor antagonist | NMDA receptor | |
| Namenda | MEMANTINE | AbbVie | marketed | N-methyl-D-aspartate Receptor Antagonist | Glutamate NMDA receptor; GRIN1/GRIN2A | 2003-01-01 |
| Felbatol | FELBAMATE | Mylan Speciality Lp | marketed | Anti-epileptic Agent [EPC] | NMDA receptor-ionophore complex | 1993-01-01 |
| QUINIDINE | QUINIDINE | marketed | sigma-1 receptor, NMDA receptor, CYP2D6 | 1950-01-01 | ||
| Methadone Hydrochloride | METHADONE | Specgx Llc | marketed | Opioid Agonist | mu-opioid receptors, NMDA receptor | 1947-01-01 |
| Ketamine with propofol | Ketamine with propofol | Henry M. Jackson Foundation for the Advancement of Military Medicine | marketed | Anesthetic combination | NMDA receptor (ketamine); GABA-A receptor (propofol) | |
| ketamine and propofol | ketamine and propofol | Ain Shams University | marketed | Intravenous anesthetic combination | NMDA receptor (ketamine); GABA-A receptor (propofol) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (NMDA receptor antagonist class)
- Turku University Hospital · 3 drugs in this class
- H. Lundbeck A/S · 2 drugs in this class
- Ciusss de L'Est de l'Île de Montréal · 2 drugs in this class
- Shalvata Mental Health Center · 2 drugs in this class
- New York State Psychiatric Institute · 2 drugs in this class
- Auris Medical AG · 1 drug in this class
- AstraZeneca · 1 drug in this class
- Alameda Health System · 1 drug in this class
- Centre Hospitalier Universitaire de Nice · 1 drug in this class
- Asker & Baerum Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Memantine (Ebixa) — Competitive Intelligence Brief. https://druglandscape.com/ci/memantine-ebixa. Accessed 2026-05-13.
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