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MCI-186 in open label phase — Competitive Intelligence Brief

MCI-186 in open label phase (MCI-186 in open label phase) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Free radical scavenger. Area: Neuroprotection.

phase 3 Free radical scavenger Neuroprotection Small molecule Live · refreshed every 30 min

Target snapshot

MCI-186 in open label phase (MCI-186 in open label phase) — Tanabe Pharma Corporation. MCI-186 is a free radical scavenger.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
MCI-186 in open label phase TARGET MCI-186 in open label phase Tanabe Pharma Corporation phase 3 Free radical scavenger
Edaravone Dexborneol Edaravone Dexborneol First Affiliated Hospital, Sun Yat-Sen University marketed Free radical scavenger combination
Radicava ORS Radicava ORS Shanghai Auzone Biological Technology Co., Ltd. marketed Free radical scavenger; antioxidant Free radicals (hydroxyl radicals); non-selective antioxidant mechanism
Compound Edaravone Injection Compound Edaravone Injection Jiangsu Simcere Pharmaceutical Co., Ltd. phase 3 Free radical scavenger / Antioxidant Hydroxyl radicals and reactive oxygen species
N-Acetylcysteine Amide N-Acetylcysteine Amide Nacuity Pharmaceuticals, Inc. phase 3 Antioxidant / Free radical scavenger Intracellular glutathione synthesis; free radicals / reactive oxygen species
MCI-186 MCI-186 Tanabe Pharma Corporation phase 3 Free radical scavenger; antioxidant Reactive oxygen species (ROS); hydroxyl radicals; peroxynitrite
Edaravone Dexborneol Sublingual Tablets Edaravone Dexborneol Sublingual Tablets Peking Union Medical College Hospital phase 3 Free radical scavenger with permeation enhancer Hydroxyl radicals and reactive oxygen species (ROS)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Free radical scavenger class)

  1. Tanabe Pharma Corporation · 1 drug in this class

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Cite this brief

Drug Landscape (2026). MCI-186 in open label phase — Competitive Intelligence Brief. https://druglandscape.com/ci/mci-186-in-open-label-phase. Accessed 2026-05-16.

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