Who are maintenance of anaesthesia with propofol's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Zulresso, Onfi, Lusedra, Campral, Sonata, Suprane.

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Last reviewed 2026-05-18 · How we verify

maintenance of anaesthesia with propofol — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

maintenance of anaesthesia with propofol (maintenance of anaesthesia with propofol) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Sedative-hypnotic agent. Area: Anaesthesia.

marketed Sedative-hypnotic agent GABA-A receptor Anaesthesia Small molecule Live · refreshed every 30 min

Target snapshot

maintenance of anaesthesia with propofol (maintenance of anaesthesia with propofol) — Centre Hospitalier Universitaire Dijon. Propofol is a sedative-hypnotic agent that enhances inhibitory GABAergic neurotransmission in the central nervous system to maintain general anaesthesia.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
maintenance of anaesthesia with propofol TARGET	maintenance of anaesthesia with propofol	Centre Hospitalier Universitaire Dijon	marketed	Sedative-hypnotic agent	GABA-A receptor
Zulresso	BREXANOLONE	Sage Therap	marketed	Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator	GABA-A receptor alpha-1/beta-2/gamma-2	2019-01-01
Onfi	CLOBAZAM	Lundbeck Pharms Llc	marketed	Benzodiazepine [EPC]	GABA-A receptor alpha-1/beta-2/gamma-2	2011-01-01
Lusedra	FOSPROPOFOL		marketed	fospropofol	GABA-A receptor	2008-01-01
Campral	ACAMPROSATE	Allergan/AbbVie	marketed	acamprosate	GABA-A receptor alpha-1/beta-3/gamma-2	2004-01-01
Sonata	ZALEPLON	Pfizer	marketed	gamma-Aminobutyric Acid A Receptor Agonist [EPC]	GABA-A receptor alpha-1/beta-2/gamma-2	1999-01-01
Suprane	DESFLURANE	Baxter	marketed	General Anesthetic [EPC]	GABA-A receptor; anion channel	1992-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2039-09-05 — Onfi · 12403090 · Formulation · US
2039-09-05 — Onfi · 12290597 · Formulation · US
2040-01-31 — Onfi · 11541002 · Formulation · US

Sponsor landscape (Sedative-hypnotic agent class)

Centre Hospitalier Universitaire Dijon · 1 drug in this class

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Cite this brief

Drug Landscape (2026). maintenance of anaesthesia with propofol — Competitive Intelligence Brief. https://druglandscape.com/ci/maintenance-of-anaesthesia-with-propofol. Accessed 2026-05-18.

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