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Lyrica (low dose) — Competitive Intelligence Brief
phase 3
Gabapentinoid; anticonvulsant; analgesic
Voltage-gated calcium channel alpha-2-delta subunit
Neurology; Pain Management
Small molecule
Live · refreshed every 30 min
Target snapshot
Lyrica (low dose) (Lyrica (low dose)) — KunWha Pharmaceutical Co., Ltd.. Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing the release of excitatory neurotransmitters.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Lyrica (low dose) TARGET | Lyrica (low dose) | KunWha Pharmaceutical Co., Ltd. | phase 3 | Gabapentinoid; anticonvulsant; analgesic | Voltage-gated calcium channel alpha-2-delta subunit | |
| Gabapentin immediate release | Gabapentin immediate release | Theresa Zesiewicz, MD | marketed | Anticonvulsant; gabapentinoid | Voltage-gated calcium channel alpha-2-delta subunit | |
| Gabapentin Enacarbil (GEn) | Gabapentin Enacarbil (GEn) | Cleveland Sleep Research Center | marketed | Gabapentinoid; anticonvulsant/neuropathic pain agent | Voltage-gated calcium channel alpha-2-delta subunit | |
| Acetaminophen, Gabapentin | Acetaminophen, Gabapentin | University of Saskatchewan | phase 3 | Analgesic combination (non-opioid analgesic + anticonvulsant) | Prostaglandin synthesis (acetaminophen); voltage-gated calcium channel alpha-2-delta subunit (gabapentin) | |
| Neurontin | gabapentin | Generic (originally Parke-Davis/Pfizer) | marketed | Gabapentinoid (anticonvulsant/neuropathic pain agent) | Large neutral amino acids transporter small subunit 1, Adenosine receptor A1, Alpha-2A adrenergic receptor | 1993-12-30 |
| Pregabalin and Oxcarbazepine | Pregabalin and Oxcarbazepine | Ju Seok Ryu | marketed | Anticonvulsant combination; Gabapentinoid and aromatic antiepileptic drug | Alpha-2-delta calcium channel subunit (pregabalin); voltage-gated sodium channels (oxcarbazepine) | |
| Imipramine, pregabalin | Imipramine, pregabalin | Odense University Hospital | marketed | Tricyclic antidepressant + gabapentinoid combination | Norepinephrine transporter, serotonin transporter, alpha-2-delta calcium channel subunit |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Gabapentinoid; anticonvulsant; analgesic class)
- KunWha Pharmaceutical Co., Ltd. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Lyrica (low dose) — Competitive Intelligence Brief. https://druglandscape.com/ci/lyrica-low-dose. Accessed 2026-05-16.
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