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Pregabalin and Oxcarbazepine

Ju Seok Ryu · FDA-approved active Small molecule

Pregabalin and Oxcarbazepine is a Anticonvulsant combination; Gabapentinoid and aromatic antiepileptic drug Small molecule drug developed by Ju Seok Ryu. It is currently FDA-approved for Epilepsy/seizure disorders, Neuropathic pain, Postherpetic neuralgia. Also known as: Lyrica and Oxcarb.

This combination product uses pregabalin to modulate calcium channels and reduce neurotransmitter release, while oxcarbazepine blocks sodium channels to stabilize neuronal membranes and reduce seizure activity.

This combination product uses pregabalin to modulate calcium channels and reduce neurotransmitter release, while oxcarbazepine blocks sodium channels to stabilize neuronal membranes and reduce seizure activity. Used for Epilepsy/seizure disorders, Neuropathic pain, Postherpetic neuralgia.

At a glance

Generic namePregabalin and Oxcarbazepine
Also known asLyrica and Oxcarb
SponsorJu Seok Ryu
Drug classAnticonvulsant combination; Gabapentinoid and aromatic antiepileptic drug
TargetAlpha-2-delta calcium channel subunit (pregabalin); voltage-gated sodium channels (oxcarbazepine)
ModalitySmall molecule
Therapeutic areaNeurology
PhaseFDA-approved

Mechanism of action

Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels, reducing calcium influx and decreasing the release of excitatory neurotransmitters. Oxcarbazepine blocks voltage-dependent sodium channels, stabilizing the inactive state of the channel and reducing repetitive neuronal firing. Together, these complementary mechanisms provide enhanced anticonvulsant and neuropathic pain relief effects.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

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Frequently asked questions about Pregabalin and Oxcarbazepine

What is Pregabalin and Oxcarbazepine?

Pregabalin and Oxcarbazepine is a Anticonvulsant combination; Gabapentinoid and aromatic antiepileptic drug drug developed by Ju Seok Ryu, indicated for Epilepsy/seizure disorders, Neuropathic pain, Postherpetic neuralgia.

How does Pregabalin and Oxcarbazepine work?

This combination product uses pregabalin to modulate calcium channels and reduce neurotransmitter release, while oxcarbazepine blocks sodium channels to stabilize neuronal membranes and reduce seizure activity.

What is Pregabalin and Oxcarbazepine used for?

Pregabalin and Oxcarbazepine is indicated for Epilepsy/seizure disorders, Neuropathic pain, Postherpetic neuralgia.

Who makes Pregabalin and Oxcarbazepine?

Pregabalin and Oxcarbazepine is developed and marketed by Ju Seok Ryu (see full Ju Seok Ryu pipeline at /company/ju-seok-ryu).

Is Pregabalin and Oxcarbazepine also known as anything else?

Pregabalin and Oxcarbazepine is also known as Lyrica and Oxcarb.

What drug class is Pregabalin and Oxcarbazepine in?

Pregabalin and Oxcarbazepine belongs to the Anticonvulsant combination; Gabapentinoid and aromatic antiepileptic drug class. See all Anticonvulsant combination; Gabapentinoid and aromatic antiepileptic drug drugs at /class/anticonvulsant-combination-gabapentinoid-and-aromatic-antiepileptic-drug.

What development phase is Pregabalin and Oxcarbazepine in?

Pregabalin and Oxcarbazepine is FDA-approved (marketed).

What are the side effects of Pregabalin and Oxcarbazepine?

Common side effects of Pregabalin and Oxcarbazepine include Dizziness, Somnolence, Ataxia, Hyponatremia, Headache, Weight gain.

What does Pregabalin and Oxcarbazepine target?

Pregabalin and Oxcarbazepine targets Alpha-2-delta calcium channel subunit (pregabalin); voltage-gated sodium channels (oxcarbazepine) and is a Anticonvulsant combination; Gabapentinoid and aromatic antiepileptic drug.

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