Last reviewed · How we verify
LY3537031 — Competitive Intelligence Brief
phase 3
GLP-1/GIP receptor dual agonist
GLP-1R, GIPR
Diabetes, Obesity
Small molecule
Live · refreshed every 30 min
Target snapshot
LY3537031 (LY3537031) — Eli Lilly and Company. LY3537031 is a GLP-1 and GIP receptor dual agonist that activates both incretin pathways to improve glucose control and promote weight loss.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| LY3537031 TARGET | LY3537031 | Eli Lilly and Company | phase 3 | GLP-1/GIP receptor dual agonist | GLP-1R, GIPR | |
| Continue GLP/GIP | Continue GLP/GIP | The Cleveland Clinic | marketed | GLP-1/GIP receptor agonist | GLP-1R, GIPR | |
| Treatment with tirzapatide | Treatment with tirzapatide | University Medical Centre Ljubljana | marketed | GLP-1/GIP receptor agonist | GLP-1R, GIPR | |
| AC2993 | AC2993 | AstraZeneca | phase 3 | Dual GLP-1/GIP receptor agonist | GLP-1R, GIPR | |
| IcoSema | IcoSema | Novo Nordisk A/S | phase 3 | GLP-1/GIP receptor agonist | GLP-1R, GIPR | |
| DA5221-T2 | DA5221-T2 | Dong-A ST Co., Ltd. | phase 3 | GLP-1/GIP receptor agonist | GLP-1R, GIPR | |
| DA5221-B2 | DA5221-B2 | Dong-A ST Co., Ltd. | phase 3 | GLP-1/GIP receptor agonist | GLP-1R, GIPR |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (GLP-1/GIP receptor dual agonist class)
- Eli Lilly and Company · 1 drug in this class
Subscribe to ongoing alerts
Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:
- LY3537031 CI watch — RSS
- LY3537031 CI watch — Atom
- LY3537031 CI watch — JSON
- LY3537031 alone — RSS
- Whole GLP-1/GIP receptor dual agonist class — RSS
Cite this brief
Drug Landscape (2026). LY3537031 — Competitive Intelligence Brief. https://druglandscape.com/ci/ly3537031. Accessed 2026-06-10.
Build your own brief
Pick any drug + add comparators:
https://druglandscape.com/ci/{slug}— auto-detected competitorshttps://druglandscape.com/ci/{slug}?vs=drug1,drug2,drug3— explicit comparators- Brand names auto-resolve:
/ci/keytruda→ 301 →/ci/pembrolizumab
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing