Who are Lotrel (amlodipine/benazepril)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Lercanidipine/enalapril fixed combination, Amlodipine Besylate / Benazepril Hydrochloride.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-16 · How we verify

Lotrel (amlodipine/benazepril) — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Lotrel (amlodipine/benazepril) (Lotrel (amlodipine/benazepril)) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Calcium channel blocker / ACE inhibitor combination. Area: Cardiovascular.

marketed Calcium channel blocker / ACE inhibitor combination L-type calcium channels (amlodipine); Angiotensin-converting enzyme (benazepril) Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Lotrel (amlodipine/benazepril) (Lotrel (amlodipine/benazepril)) — Abbott. Lotrel combines a calcium channel blocker and an ACE inhibitor to lower blood pressure through two complementary pathways: relaxing blood vessel smooth muscle and reducing angiotensin II-mediated vasoconstriction.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Lotrel (amlodipine/benazepril) TARGET	Lotrel (amlodipine/benazepril)	Abbott	marketed	Calcium channel blocker / ACE inhibitor combination	L-type calcium channels (amlodipine); Angiotensin-converting enzyme (benazepril)
Lercanidipine/enalapril fixed combination	Lercanidipine/enalapril fixed combination	Meir Medical Center	marketed	Calcium channel blocker / ACE inhibitor combination	L-type voltage-gated calcium channels; Angiotensin-converting enzyme (ACE)
Amlodipine Besylate / Benazepril Hydrochloride	Amlodipine Besylate / Benazepril Hydrochloride	Dr. Reddy's Laboratories Limited	marketed	Calcium channel blocker / ACE inhibitor combination	L-type calcium channels; Angiotensin-converting enzyme (ACE)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Calcium channel blocker / ACE inhibitor combination class)

Abbott · 1 drug in this class
Dr. Reddy's Laboratories Limited · 1 drug in this class
Meir Medical Center · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Lotrel (amlodipine/benazepril) — Competitive Intelligence Brief. https://druglandscape.com/ci/lotrel-amlodipine-benazepril. Accessed 2026-05-16.

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