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Losartan (+) amlodipine — Competitive Intelligence Brief
marketed
Angiotensin II receptor blocker + calcium channel blocker combination
AT1 receptor (losartan); L-type voltage-gated calcium channel (amlodipine)
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
Losartan (+) amlodipine (Losartan (+) amlodipine) — Organon and Co. This combination blocks angiotensin II receptors and calcium channels to reduce blood pressure through vasodilation and decreased vascular resistance.
Comparator set (5 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Losartan (+) amlodipine TARGET | Losartan (+) amlodipine | Organon and Co | marketed | Angiotensin II receptor blocker + calcium channel blocker combination | AT1 receptor (losartan); L-type voltage-gated calcium channel (amlodipine) | |
| Telmisartan + Amlodipine | Telmisartan + Amlodipine | Daewon Pharmaceutical Co., Ltd. | marketed | Angiotensin II receptor blocker + Calcium channel blocker combination | AT1 receptor (angiotensin II type 1 receptor) and L-type voltage-gated calcium channels | |
| Azilsartan Medoxomil and amlodipine | Azilsartan Medoxomil and amlodipine | Takeda | phase 3 | Angiotensin II receptor blocker + calcium channel blocker combination | AT1 receptor (angiotensin II type 1 receptor) and L-type voltage-gated calcium channels | |
| AZM X mg + AML Y mg | AZM X mg + AML Y mg | Celltrion | phase 3 | Angiotensin II receptor blocker + Calcium channel blocker combination | AT1 receptor (azilsartan); L-type calcium channel (amlodipine) | |
| Valsartan + Amlodipine besilate | Valsartan + Amlodipine besilate | Novartis | phase 3 | Angiotensin II receptor blocker + Calcium channel blocker combination | AT1 receptor (angiotensin II type 1 receptor) and L-type voltage-gated calcium channels | |
| Fimasartan and Amlodipine | Fimasartan and Amlodipine | Boryung Pharmaceutical Co., Ltd | phase 3 | Angiotensin II receptor blocker + Calcium channel blocker combination | AT1 receptor (fimasartan); L-type calcium channel (amlodipine) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Angiotensin II receptor blocker + calcium channel blocker combination class)
- Organon and Co · 1 drug in this class
- Takeda · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Losartan (+) amlodipine — Competitive Intelligence Brief. https://druglandscape.com/ci/losartan-amlodipine. Accessed 2026-05-16.
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