local infiltration — Competitive Intelligence Brief

local infiltration (local infiltration) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Anesthesia.

marketed Local anesthetic Anesthesia Small molecule

Target snapshot

local infiltration (local infiltration) — The Catholic University of Korea. Local infiltration is a surgical/anesthetic technique that delivers anesthetic agents directly into tissue at the site of procedure to block pain sensation in that specific area.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
local infiltration TARGET	local infiltration	The Catholic University of Korea	marketed	Local anesthetic
Tetracaine Hydrochloride	TETRACAINE	Alcon Labs	marketed	Ester Local Anesthetic	Sodium channel protein type 7 subunit alpha	2005-01-01
Septocaine	ARTICAINE		marketed	Amide Local Anesthetic	Sodium channel alpha subunits; brain (Types I, II, III)	2000-01-01
Naropin	ROPIVACAINE	Fresenius Kabi	marketed	Amide Local Anesthetic	Sodium channel protein type 5 subunit alpha	1996-01-01
Bupivacaine Hydrochloride	Bupivacaine Hydrochloride	Pfizer	marketed	Amide-type local anesthetic	Nerve sodium channels	1972-01-01
Bupivacaine Hydrochloride And Epinephrine	Bupivacaine Hydrochloride	Pfizer	marketed	Local anesthetic	Sodium channels	1972-01-01
Bupivacaine Hydrochloride And Epinephrine	Bupivacaine Hydrochloride	Pfizer	marketed	Amide local anesthetic	Nerve sodium channels	1972-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

• 2029-05-20 — Bupivacaine Hydrochloride · RE47826 · US
• 2034-03-13 — Bupivacaine Hydrochloride · 10398686 · US
• 2034-03-13 — Bupivacaine Hydrochloride · 11253504 · US
• 2034-03-13 — Bupivacaine Hydrochloride · 9592227 · US
• 2034-03-13 — Bupivacaine Hydrochloride · 9744163 · US
• 2034-03-13 — Bupivacaine Hydrochloride · 9913909 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 9694079 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 9801945 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 10098957 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 10213510 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 10632199 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 10898575 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 10980886 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 11083730 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 11083797 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 11413350 · US
• 2041-01-12 — Bupivacaine Hydrochloride · 11400019 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11452691 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11179336 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11278494 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11304904 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11311486 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11357727 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11426348 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11033495 · US

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class