Who are Lisinopril + HCTZ's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Captopril,Hydrochlorothiazide.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-16 · How we verify

Lisinopril + HCTZ — Competitive Intelligence Brief

Lisinopril + HCTZ (Lisinopril + HCTZ) competitive landscape: 1 comparator, recent regulatory actions, upcoming PDUFA, patent timeline. Class: ACE inhibitor + thiazide diuretic combination. Area: Cardiovascular.

phase 3 ACE inhibitor + thiazide diuretic combination Angiotensin-converting enzyme (ACE); sodium-chloride cotransporter (NCCT) Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Lisinopril + HCTZ (Lisinopril + HCTZ) — St. Paul Heart Clinic. Lisinopril inhibits angiotensin-converting enzyme to reduce blood pressure, while HCTZ is a thiazide diuretic that lowers blood pressure by reducing fluid volume and sodium reabsorption.

Comparator set (1 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Lisinopril + HCTZ TARGET	Lisinopril + HCTZ	St. Paul Heart Clinic	phase 3	ACE inhibitor + thiazide diuretic combination	Angiotensin-converting enzyme (ACE); sodium-chloride cotransporter (NCCT)
Captopril,Hydrochlorothiazide	Captopril,Hydrochlorothiazide	West China Hospital	marketed	ACE inhibitor + thiazide diuretic combination	ACE (angiotensin-converting enzyme); sodium-chloride cotransporter in distal convoluted tubule

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (ACE inhibitor + thiazide diuretic combination class)

St. Paul Heart Clinic · 1 drug in this class
West China Hospital · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Lisinopril + HCTZ — Competitive Intelligence Brief. https://druglandscape.com/ci/lisinopril-hctz. Accessed 2026-05-16.

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