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Levonorgestrel/Ethinyl Estradiol — Competitive Intelligence Brief
Target snapshot
Levonorgestrel/Ethinyl Estradiol (Levonorgestrel/Ethinyl Estradiol) — Wyeth is now a wholly owned subsidiary of Pfizer. This combination oral contraceptive suppresses ovulation by inhibiting the luteinizing hormone surge through progestin and estrogen feedback on the hypothalamic-pituitary axis.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Levonorgestrel/Ethinyl Estradiol TARGET | Levonorgestrel/Ethinyl Estradiol | Wyeth is now a wholly owned subsidiary of Pfizer | marketed | Combined oral contraceptive | Progesterone receptor, estrogen receptor alpha and beta | |
| Ethinyl Estradiol + Cyproterone acetate | Ethinyl Estradiol + Cyproterone acetate | Fundação Educacional Serra dos Órgãos | marketed | Combined oral contraceptive with anti-androgenic activity | Androgen receptor (cyproterone acetate); estrogen receptor (ethinyl estradiol); gonadotropin suppression | |
| OCR | OCR | Hoffmann-La Roche | marketed | Combined oral contraceptive | Estrogen receptor and progesterone receptor | |
| desogestrel/ethinyl estradiol | desogestrel/ethinyl estradiol | Teva Branded Pharmaceutical Products R&D, Inc. | marketed | Combined oral contraceptive | Progesterone receptor, estrogen receptor | |
| Ethinylestradiol / Dienogest | Ethinylestradiol / Dienogest | University of Palermo | marketed | Combined oral contraceptive | Estrogen receptor, progesterone receptor | |
| Nomegestrol Acetate / Estradiol | Nomegestrol Acetate / Estradiol | University of Palermo | marketed | Combined oral contraceptive | Progesterone receptor, Estrogen receptor | |
| norelgestromin + ethinyl estradiol | norelgestromin + ethinyl estradiol | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | marketed | Combined oral contraceptive (progestin + estrogen) | Progesterone receptor, estrogen receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Combined oral contraceptive class)
- University of Palermo · 3 drugs in this class
- Teva Branded Pharmaceutical Products R&D, Inc. · 2 drugs in this class
- Organon and Co · 2 drugs in this class
- HRA Pharma · 1 drug in this class
- Hansoh BioMedical R&D Company · 1 drug in this class
- Helsinki University Central Hospital · 1 drug in this class
- Hoffmann-La Roche · 1 drug in this class
- IVI Madrid · 1 drug in this class
- Leiden University Medical Center · 1 drug in this class
- Massachusetts General Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Levonorgestrel/Ethinyl Estradiol — Competitive Intelligence Brief. https://druglandscape.com/ci/levonorgestrel-ethinyl-estradiol. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing