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larotaxel (RPR109881, XRP9881) — Competitive Intelligence Brief
phase 3
Taxane (microtubule stabilizer)
β-tubulin
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
larotaxel (RPR109881, XRP9881) (larotaxel (RPR109881, XRP9881)) — Sanofi. Larotaxel is a microtubule-stabilizing taxane that binds to β-tubulin and prevents microtubule depolymerization, leading to cell cycle arrest and apoptosis in cancer cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| larotaxel (RPR109881, XRP9881) TARGET | larotaxel (RPR109881, XRP9881) | Sanofi | phase 3 | Taxane (microtubule stabilizer) | β-tubulin | |
| VLI | VLI | Spectrum Pharmaceuticals, Inc | marketed | Vinca alkaloid | β-tubulin | |
| Paclitaxel (Pac) | Paclitaxel (Pac) | Aravive, Inc. | marketed | Taxane; microtubule stabilizer | β-tubulin / microtubules | |
| Placebo plus Docetaxel | Placebo plus Docetaxel | Infinity Pharmaceuticals, Inc. | marketed | Taxane (microtubule stabilizer) | Microtubules (β-tubulin) | |
| Paclitaxel (albumin-bound) | Paclitaxel (albumin-bound) | Dai, Guanghai | marketed | Taxane; microtubule stabilizer | β-tubulin (microtubule) | |
| ''albendazole'' and ''ivermectin'' | ''albendazole'' and ''ivermectin'' | Centre d'Appui à la lutte contre la Maladie | marketed | Antihelmintic/Antiparasitic agents | β-tubulin (albendazole); glutamate-gated chloride channels (ivermectin) | |
| Paclitaxel protein bound | Paclitaxel protein bound | Barts & The London NHS Trust | marketed | Taxane; microtubule stabilizer | β-tubulin (microtubule) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Taxane (microtubule stabilizer) class)
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · 1 drug in this class
- Eli Lilly and Company · 1 drug in this class
- Infinity Pharmaceuticals, Inc. · 1 drug in this class
- Sanofi · 1 drug in this class
- University of Turin, Italy · 1 drug in this class
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Cite this brief
Drug Landscape (2026). larotaxel (RPR109881, XRP9881) — Competitive Intelligence Brief. https://druglandscape.com/ci/larotaxel-rpr109881-xrp9881. Accessed 2026-05-17.
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