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larotaxel (RPR109881, XRP9881) — Competitive Intelligence Brief

larotaxel (RPR109881, XRP9881) (larotaxel (RPR109881, XRP9881)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Taxane (microtubule stabilizer). Area: Oncology.

phase 3 Taxane (microtubule stabilizer) β-tubulin Oncology Small molecule Live · refreshed every 30 min

Target snapshot

larotaxel (RPR109881, XRP9881) (larotaxel (RPR109881, XRP9881)) — Sanofi. Larotaxel is a microtubule-stabilizing taxane that binds to β-tubulin and prevents microtubule depolymerization, leading to cell cycle arrest and apoptosis in cancer cells.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
larotaxel (RPR109881, XRP9881) TARGET larotaxel (RPR109881, XRP9881) Sanofi phase 3 Taxane (microtubule stabilizer) β-tubulin
VLI VLI Spectrum Pharmaceuticals, Inc marketed Vinca alkaloid β-tubulin
Paclitaxel (Pac) Paclitaxel (Pac) Aravive, Inc. marketed Taxane; microtubule stabilizer β-tubulin / microtubules
Placebo plus Docetaxel Placebo plus Docetaxel Infinity Pharmaceuticals, Inc. marketed Taxane (microtubule stabilizer) Microtubules (β-tubulin)
Paclitaxel (albumin-bound) Paclitaxel (albumin-bound) Dai, Guanghai marketed Taxane; microtubule stabilizer β-tubulin (microtubule)
''albendazole'' and ''ivermectin'' ''albendazole'' and ''ivermectin'' Centre d'Appui à la lutte contre la Maladie marketed Antihelmintic/Antiparasitic agents β-tubulin (albendazole); glutamate-gated chloride channels (ivermectin)
Paclitaxel protein bound Paclitaxel protein bound Barts & The London NHS Trust marketed Taxane; microtubule stabilizer β-tubulin (microtubule)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Taxane (microtubule stabilizer) class)

  1. Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · 1 drug in this class
  2. Eli Lilly and Company · 1 drug in this class
  3. Infinity Pharmaceuticals, Inc. · 1 drug in this class
  4. Sanofi · 1 drug in this class
  5. University of Turin, Italy · 1 drug in this class

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Cite this brief

Drug Landscape (2026). larotaxel (RPR109881, XRP9881) — Competitive Intelligence Brief. https://druglandscape.com/ci/larotaxel-rpr109881-xrp9881. Accessed 2026-05-17.

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