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KK8398 — Competitive Intelligence Brief

KK8398 (KK8398) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Complement C5a receptor antagonist. Area: Immunology.

phase 3 Complement C5a receptor antagonist C5aR1 (C5a receptor 1) Immunology Small molecule Live · refreshed every 30 min

Target snapshot

KK8398 (KK8398) — Kyowa Kirin Co., Ltd.. KK8398 is a complement C5a receptor antagonist that blocks the C5a-C5aR1 signaling pathway to reduce inflammatory cell recruitment and activation.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
KK8398 TARGET KK8398 Kyowa Kirin Co., Ltd. phase 3 Complement C5a receptor antagonist C5aR1 (C5a receptor 1)
LJPC-501 LJPC-501 La Jolla Pharmaceutical Company phase 3 Complement C5a receptor antagonist C5a receptor (C5aR)
MP-513 MP-513 Tanabe Pharma Corporation phase 3 Complement C5a receptor antagonist C5a receptor (C5aR)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Complement C5a receptor antagonist class)

  1. Astellas Pharma Global Development, Inc. · 1 drug in this class
  2. Kyowa Kirin Co., Ltd. · 1 drug in this class
  3. La Jolla Pharmaceutical Company · 1 drug in this class
  4. Tanabe Pharma Corporation · 1 drug in this class

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Cite this brief

Drug Landscape (2026). KK8398 — Competitive Intelligence Brief. https://druglandscape.com/ci/kk8398. Accessed 2026-05-13.

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