Who are ketamine sedation versus midazolam sedation's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Namenda, Felbatol, QUINIDINE, Methadone Hydrochloride, Naloxone + Ketamine, Intravenous Ketamine.

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Last reviewed 2026-05-17 · How we verify

ketamine sedation versus midazolam sedation — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

ketamine sedation versus midazolam sedation (ketamine sedation versus midazolam sedation) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Anesthetic. Area: Anesthesiology.

phase 3 Anesthetic NMDA receptor Anesthesiology Small molecule Live · refreshed every 30 min

Target snapshot

ketamine sedation versus midazolam sedation (ketamine sedation versus midazolam sedation) — Universidad de Colima. Ketamine acts as an NMDA receptor antagonist, blocking the action of glutamate in the brain.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
ketamine sedation versus midazolam sedation TARGET	ketamine sedation versus midazolam sedation	Universidad de Colima	phase 3	Anesthetic	NMDA receptor
Namenda	MEMANTINE	AbbVie	marketed	N-methyl-D-aspartate Receptor Antagonist	Glutamate NMDA receptor; GRIN1/GRIN2A	2003-01-01
Felbatol	FELBAMATE	Mylan Speciality Lp	marketed	Anti-epileptic Agent [EPC]	NMDA receptor-ionophore complex	1993-01-01
QUINIDINE	QUINIDINE		marketed		sigma-1 receptor, NMDA receptor, CYP2D6	1950-01-01
Methadone Hydrochloride	METHADONE	Specgx Llc	marketed	Opioid Agonist	mu-opioid receptors, NMDA receptor	1947-01-01
Naloxone + Ketamine	Naloxone + Ketamine	Ullevaal University Hospital	marketed	Opioid antagonist + NMDA receptor antagonist combination	Opioid receptors (mu, delta, kappa) and NMDA receptor
Intravenous Ketamine	Intravenous Ketamine	Rebecca Price	marketed	Dissociative anesthetic	NMDA receptors

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Anesthetic class)

Express Specialty Pharmacy · 1 drug in this class
Nantes University Hospital · 1 drug in this class
The University of Texas Health Science Center, Houston · 1 drug in this class
Universidad de Colima · 1 drug in this class
University Hospital, Montpellier · 1 drug in this class

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Cite this brief

Drug Landscape (2026). ketamine sedation versus midazolam sedation — Competitive Intelligence Brief. https://druglandscape.com/ci/ketamine-sedation-versus-midazolam-sedation. Accessed 2026-05-17.

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