Who are Keppra XR (Levetiracetam XR)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Adjunctive Zonisamide, Low dose oxcarbazepine, Lamotrigine (drug), Standard dose lamotrigine, Replacement with Zonisamide, Low dose carbamazepine.

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Last reviewed 2026-05-17 · How we verify

Keppra XR (Levetiracetam XR) — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Keppra XR (Levetiracetam XR) (Keppra XR (Levetiracetam XR)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Anticonvulsant / Antiepileptic drug. Area: Neurology.

phase 3 Anticonvulsant / Antiepileptic drug SV2A (synaptic vesicle protein 2A) Neurology Small molecule Live · refreshed every 30 min

Target snapshot

Keppra XR (Levetiracetam XR) (Keppra XR (Levetiracetam XR)) — UCB Pharma. Levetiracetam reduces seizure activity by binding to synaptic vesicle protein SV2A and modulating neurotransmitter release.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Keppra XR (Levetiracetam XR) TARGET	Keppra XR (Levetiracetam XR)	UCB Pharma	phase 3	Anticonvulsant / Antiepileptic drug	SV2A (synaptic vesicle protein 2A)
Adjunctive Zonisamide	Adjunctive Zonisamide	Eisai Inc.	marketed	Anticonvulsant / Antiepileptic drug	Voltage-gated sodium channels, T-type calcium channels, carbonic anhydrase
Low dose oxcarbazepine	Low dose oxcarbazepine	Mario Negri Institute for Pharmacological Research	marketed	Anticonvulsant / Antiepileptic drug	Voltage-gated sodium channels; high-voltage-activated calcium channels
Lamotrigine (drug)	Lamotrigine (drug)	MaineHealth	marketed	Anticonvulsant / Antiepileptic drug	Voltage-gated sodium channels; glutamate release inhibition
Standard dose lamotrigine	Standard dose lamotrigine	Mario Negri Institute for Pharmacological Research	marketed	Anticonvulsant / Antiepileptic drug	Voltage-gated sodium channels; glutamate release inhibition
Replacement with Zonisamide	Replacement with Zonisamide	Eisai Inc.	marketed	Anticonvulsant / Antiepileptic drug	Voltage-gated sodium channels, T-type calcium channels
Low dose carbamazepine	Low dose carbamazepine	Mario Negri Institute for Pharmacological Research	marketed	Anticonvulsant / Antiepileptic drug	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Anticonvulsant / Antiepileptic drug class)

Mario Negri Institute for Pharmacological Research · 3 drugs in this class
Eisai Inc. · 2 drugs in this class
Affiliated Hospital of Nantong University · 1 drug in this class
GlaxoSmithKline · 1 drug in this class
MaineHealth · 1 drug in this class
UCB Pharma · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Keppra XR (Levetiracetam XR) — Competitive Intelligence Brief. https://druglandscape.com/ci/keppra-xr-levetiracetam-xr. Accessed 2026-05-17.

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