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JNJ16269110 — Competitive Intelligence Brief
phase 2
Glucagon receptor antagonist
Glucagon receptor
Diabetes
Small molecule
Live · refreshed every 30 min
Target snapshot
JNJ16269110 (JNJ16269110) — Johnson & Johnson Pharmaceutical Research & Development, L.L.C.. JNJ16269110 is a selective and potent antagonist of the human glucagon receptor.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| JNJ16269110 TARGET | JNJ16269110 | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | phase 2 | Glucagon receptor antagonist | Glucagon receptor | |
| Zegalogue | DASIGLUCAGON | Zealand Pharma | marketed | Antihypoglycemic Agent [EPC] | Glucagon receptor | 2021-01-01 |
| Low-Dose Glucagon | Low-Dose Glucagon | Steno Diabetes Center Copenhagen | marketed | Glucagon receptor agonist | Glucagon receptor (GCGR) | |
| Glucagon 12.5ng/kg/min | Glucagon 12.5ng/kg/min | Cambridge University Hospitals NHS Foundation Trust | marketed | Glucagon receptor agonist | Glucagon receptor (GCGR) | |
| morphine and glucagon | morphine and glucagon | National Taiwan University Hospital | marketed | Opioid analgesic + glucagon (hormone) | Mu-opioid receptor (morphine); glucagon receptor (glucagon) | |
| NNC6019-0001 | NNC6019-0001 | Novo Nordisk A/S | phase 3 | Glucagon receptor antagonist | Glucagon receptor (GCGR) | |
| MK-0524B | MK-0524B | Merck Sharp & Dohme LLC | phase 3 | Glucagon receptor antagonist | Glucagon receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Glucagon receptor antagonist class)
- Merck Sharp & Dohme LLC · 2 drugs in this class
- Alizyme · 2 drugs in this class
- Claes-Göran Östenson · 1 drug in this class
- Gan and Lee Pharmaceuticals, USA · 1 drug in this class
- GlaxoSmithKline · 1 drug in this class
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · 1 drug in this class
- AbbVie (prior sponsor, Abbott) · 1 drug in this class
- Novo Nordisk A/S · 1 drug in this class
- Allergan · 1 drug in this class
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Cite this brief
Drug Landscape (2026). JNJ16269110 — Competitive Intelligence Brief. https://druglandscape.com/ci/jnj16269110. Accessed 2026-06-10.
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