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Ivermectin on Day 1 — Competitive Intelligence Brief
phase 3
Macrocyclic lactone antiparasitic
Glutamate-gated chloride channels (GluCl)
Infectious Disease / Parasitology
Small molecule
Live · refreshed every 30 min
Target snapshot
Ivermectin on Day 1 (Ivermectin on Day 1) — Lihir Medical Centre. Ivermectin is a macrocyclic lactone that binds to glutamate-gated chloride channels in parasites, causing paralysis and death.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Ivermectin on Day 1 TARGET | Ivermectin on Day 1 | Lihir Medical Centre | phase 3 | Macrocyclic lactone antiparasitic | Glutamate-gated chloride channels (GluCl) | |
| Oral ivermectin | Oral ivermectin | University of Oxford | marketed | Macrocyclic lactone antiparasitic | Glutamate-gated chloride channels (GluCl) | |
| Ivermectin 400 µg/kg | Ivermectin 400 µg/kg | Assistance Publique - Hôpitaux de Paris | phase 3 | Macrocyclic lactone antiparasitic | Glutamate-gated chloride channels (GluCl) | |
| Soolantra® Ivermectin cream 1% | Soolantra® Ivermectin cream 1% | Zydus Worldwide DMCC | phase 3 | Macrocyclic lactone antiparasitic / anti-inflammatory | Glutamate-gated chloride channels; innate immune modulators |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Macrocyclic lactone antiparasitic class)
- Assistance Publique - Hôpitaux de Paris · 1 drug in this class
- Lihir Medical Centre · 1 drug in this class
- University of Oxford · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Ivermectin on Day 1 — Competitive Intelligence Brief. https://druglandscape.com/ci/ivermectin-on-day-1. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing