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Ivacaftor and Symdeko — Competitive Intelligence Brief
marketed
CFTR modulator (potentiator and corrector combination)
CFTR (Cystic Fibrosis Transmembrane Conductance Regulator)
Pulmonary/Respiratory
Small molecule
Live · refreshed every 30 min
Target snapshot
Ivacaftor and Symdeko (Ivacaftor and Symdeko) — University of Alabama at Birmingham. Ivacaftor is a CFTR potentiator that increases the opening probability of the cystic fibrosis transmembrane conductance regulator (CFTR) channel, while Symdeko combines ivacaftor with lumacaftor, a CFTR corrector that helps misfolded CFTR protein reach the cell surface.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Ivacaftor and Symdeko TARGET | Ivacaftor and Symdeko | University of Alabama at Birmingham | marketed | CFTR modulator (potentiator and corrector combination) | CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (CFTR modulator (potentiator and corrector combination) class)
- University of Alabama at Birmingham · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Ivacaftor and Symdeko — Competitive Intelligence Brief. https://druglandscape.com/ci/ivacaftor-and-symdeko. Accessed 2026-05-17.
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