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Ivacaftor and Symdeko — Competitive Intelligence Brief

Ivacaftor and Symdeko (Ivacaftor and Symdeko) competitive landscape: 0 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: CFTR modulator (potentiator and corrector combination). Area: Pulmonary/Respiratory.

marketed CFTR modulator (potentiator and corrector combination) CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) Pulmonary/Respiratory Small molecule Live · refreshed every 30 min

Target snapshot

Ivacaftor and Symdeko (Ivacaftor and Symdeko) — University of Alabama at Birmingham. Ivacaftor is a CFTR potentiator that increases the opening probability of the cystic fibrosis transmembrane conductance regulator (CFTR) channel, while Symdeko combines ivacaftor with lumacaftor, a CFTR corrector that helps misfolded CFTR protein reach the cell surface.

Comparator set

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Ivacaftor and Symdeko TARGET Ivacaftor and Symdeko University of Alabama at Birmingham marketed CFTR modulator (potentiator and corrector combination) CFTR (Cystic Fibrosis Transmembrane Conductance Regulator)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (CFTR modulator (potentiator and corrector combination) class)

  1. University of Alabama at Birmingham · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Ivacaftor and Symdeko — Competitive Intelligence Brief. https://druglandscape.com/ci/ivacaftor-and-symdeko. Accessed 2026-05-17.

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