Who are Istradefylline (KW-6002)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Regadenoson myocardial perfusion imaging, Regadenoson (Lexiscan), Regadenoson MRI myocardial blood flow, Regadenoson peripheral - peripheral, Pharmacological stress agents, Regadenoson peripheral - central.

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Last reviewed 2026-05-16 · How we verify

Istradefylline (KW-6002) — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Istradefylline (KW-6002) (Istradefylline (KW-6002)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Adenosine A2A receptor antagonist. Area: Neurology.

phase 3 Adenosine A2A receptor antagonist Adenosine A2A receptor Neurology Small molecule Live · refreshed every 30 min

Target snapshot

Istradefylline (KW-6002) (Istradefylline (KW-6002)) — Kyowa Kirin, Inc.. Istradefylline is an adenosine A2A receptor antagonist that blocks inhibitory signaling in the basal ganglia, thereby enhancing dopaminergic motor control.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Istradefylline (KW-6002) TARGET	Istradefylline (KW-6002)	Kyowa Kirin, Inc.	phase 3	Adenosine A2A receptor antagonist	Adenosine A2A receptor
Regadenoson myocardial perfusion imaging	Regadenoson myocardial perfusion imaging	University of Colorado, Denver	marketed	Adenosine A2A receptor agonist	Adenosine A2A receptor
Regadenoson (Lexiscan)	Regadenoson (Lexiscan)	Brigham and Women's Hospital	marketed	Adenosine A2A receptor agonist	Adenosine A2A receptor
Regadenoson MRI myocardial blood flow	Regadenoson MRI myocardial blood flow	University of Colorado, Denver	marketed	Adenosine A2A receptor agonist	Adenosine A2A receptor
Regadenoson peripheral - peripheral	Regadenoson peripheral - peripheral	Lokien van Nunen	phase 3	Adenosine A2A receptor agonist	Adenosine A2A receptor
Pharmacological stress agents	Pharmacological stress agents	GE Healthcare	phase 3	Cardiac stress agents	Adenosine A2A receptor (adenosine); dopamine and beta-adrenergic receptors (dobutamine); adenosine A2A receptor (regadenoson)
Regadenoson peripheral - central	Regadenoson peripheral - central	Lokien van Nunen	phase 3	Adenosine A2A receptor agonist	Adenosine A2A receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Adenosine A2A receptor antagonist class)

Apnimed · 1 drug in this class
Kyowa Kirin, Inc. · 1 drug in this class
Sosei · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Istradefylline (KW-6002) — Competitive Intelligence Brief. https://druglandscape.com/ci/istradefylline-kw-6002. Accessed 2026-05-16.

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