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ISIS-PTP1BRx — Competitive Intelligence Brief

ISIS-PTP1BRx (ISIS-PTP1BRx) competitive landscape: 0 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antisense oligonucleotide (PTP1B inhibitor). Area: Metabolic/Endocrinology.

phase 2 Antisense oligonucleotide (PTP1B inhibitor) PTP1B (Protein Tyrosine Phosphatase 1B) Metabolic/Endocrinology Small molecule Live · refreshed every 30 min

Target snapshot

ISIS-PTP1BRx (ISIS-PTP1BRx) — Ionis Pharmaceuticals, Inc.. ISIS-PTP1BRx is an antisense oligonucleotide that inhibits protein tyrosine phosphatase 1B (PTP1B) to improve insulin signaling and glucose metabolism.

Comparator set

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
ISIS-PTP1BRx TARGET ISIS-PTP1BRx Ionis Pharmaceuticals, Inc. phase 2 Antisense oligonucleotide (PTP1B inhibitor) PTP1B (Protein Tyrosine Phosphatase 1B)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antisense oligonucleotide (PTP1B inhibitor) class)

  1. Ionis Pharmaceuticals, Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). ISIS-PTP1BRx — Competitive Intelligence Brief. https://druglandscape.com/ci/isis-ptp1brx. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing