Last reviewed · How we verify
Intravenous iclaprim — Competitive Intelligence Brief
phase 3
Dihydrofolate reductase inhibitor
Dihydrofolate reductase (DHFR)
Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
Intravenous iclaprim (Intravenous iclaprim) — Arpida AG. Iclaprim is a dihydrofolate reductase (DHFR) inhibitor that disrupts bacterial folate metabolism, preventing DNA synthesis and bacterial growth.
Comparator set (4 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Intravenous iclaprim TARGET | Intravenous iclaprim | Arpida AG | phase 3 | Dihydrofolate reductase inhibitor | Dihydrofolate reductase (DHFR) | |
| Sulfamethoxazole / Trimethoprim Injectable Product | Sulfamethoxazole / Trimethoprim Injectable Product | Fundacion Clinic per a la Recerca Biomédica | marketed | Sulfonamide + dihydrofolate reductase inhibitor combination | Dihydropteroate synthase and dihydrofolate reductase | |
| Sulfamethoxazole Trimethoprim Combination | Sulfamethoxazole Trimethoprim Combination | Baylor Research Institute | marketed | Sulfonamide-dihydrofolate reductase inhibitor combination | Dihydropteroate synthase; Dihydrofolate reductase | |
| Sulfamethoxazole-Trimethoprim | Sulfamethoxazole-Trimethoprim | National Institute of Allergy and Infectious Diseases (NIAID) | marketed | Sulfonamide-dihydrofolate reductase inhibitor combination | Dihydropteroate synthase; Dihydrofolate reductase | |
| SMZ/TMP | SMZ/TMP | First Affiliated Hospital of Zhejiang University | phase 3 | Sulfonamide and dihydrofolate reductase inhibitor combination |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Dihydrofolate reductase inhibitor class)
- Arpida AG · 1 drug in this class
Subscribe to ongoing alerts
Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:
- Intravenous iclaprim CI watch — RSS
- Intravenous iclaprim CI watch — Atom
- Intravenous iclaprim CI watch — JSON
- Intravenous iclaprim alone — RSS
- Whole Dihydrofolate reductase inhibitor class — RSS
Cite this brief
Drug Landscape (2026). Intravenous iclaprim — Competitive Intelligence Brief. https://druglandscape.com/ci/intravenous-iclaprim. Accessed 2026-05-17.
Build your own brief
Pick any drug + add comparators:
https://druglandscape.com/ci/{slug}— auto-detected competitorshttps://druglandscape.com/ci/{slug}?vs=drug1,drug2,drug3— explicit comparators- Brand names auto-resolve:
/ci/keytruda→ 301 →/ci/pembrolizumab