Intraperitoneal lidocaine irrigation group — Competitive Intelligence Brief

Intraperitoneal lidocaine irrigation group (Intraperitoneal lidocaine irrigation group) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Pain management / Surgery.

marketed Local anesthetic Voltage-gated sodium channels Pain management / Surgery Small molecule

Target snapshot

Intraperitoneal lidocaine irrigation group (Intraperitoneal lidocaine irrigation group) — Chung-Ang University Hosptial, Chung-Ang University College of Medicine. Intraperitoneal lidocaine irrigation delivers a local anesthetic directly into the peritoneal cavity to reduce postoperative pain and inflammation.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Intraperitoneal lidocaine irrigation group TARGET	Intraperitoneal lidocaine irrigation group	Chung-Ang University Hosptial, Chung-Ang University College of Medicine	marketed	Local anesthetic	Voltage-gated sodium channels
Low dose carbamazepine	Low dose carbamazepine	Mario Negri Institute for Pharmacological Research	marketed	Anticonvulsant / Antiepileptic drug	Voltage-gated sodium channels
Lamotrigine + Aripiprazole	Lamotrigine + Aripiprazole	Otsuka Pharmaceutical Development & Commercialization, Inc.	marketed	Anticonvulsant/mood stabilizer + atypical antipsychotic combination	Voltage-gated sodium channels (lamotrigine); dopamine D2/D3 receptors (aripiprazole)
Lidocaine patch 1.8%	Lidocaine patch 1.8%	Scilex Pharmaceuticals, Inc.	marketed	Local anesthetic	Voltage-gated sodium channels
Low dose lamotrigine	Low dose lamotrigine	Mario Negri Institute for Pharmacological Research	marketed	Anticonvulsant / Mood stabilizer	Voltage-gated sodium channels; glutamate release modulation
Bupivacaine Hydrochloride combined with dexamethasone	Bupivacaine Hydrochloride combined with dexamethasone	Zhejiang Cancer Hospital	marketed	Local anesthetic with corticosteroid adjuvant	Voltage-gated sodium channels (bupivacaine); glucocorticoid receptor (dexamethasone)
oral suzetrigine	oral suzetrigine	University of Louisville	marketed	Selective sodium channel blocker	Voltage-gated sodium channels (Nav)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class