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Inhaled Nitric Oxide (iNO) use — Competitive Intelligence Brief
marketed
Inhaled vasodilator
Soluble guanylate cyclase
Pulmonary/Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
Inhaled Nitric Oxide (iNO) use (Inhaled Nitric Oxide (iNO) use) — The University of Texas Health Science Center, Houston. Inhaled nitric oxide is a vasodilator gas that selectively relaxes pulmonary vascular smooth muscle to reduce pulmonary hypertension and improve oxygenation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Inhaled Nitric Oxide (iNO) use TARGET | Inhaled Nitric Oxide (iNO) use | The University of Texas Health Science Center, Houston | marketed | Inhaled vasodilator | Soluble guanylate cyclase | |
| Inomax | NITRIC OXIDE | Vero Biotech Inc | marketed | Standardized Chemical Allergen [EPC] | Soluble guanylate cyclase | 1999-01-01 |
| iNO | iNO | Wake Forest University Health Sciences | marketed | Inhaled vasodilator | Soluble guanylate cyclase | |
| Crossover iNO | Crossover iNO | University of Florida | marketed | Inhaled vasodilator | Soluble guanylate cyclase (via nitric oxide signaling) | |
| iso- 5 - mononitrate | iso- 5 - mononitrate | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | marketed | Nitrate vasodilator | Soluble guanylate cyclase (via nitric oxide) | |
| Nitroglycerin (NTG) | Nitroglycerin (NTG) | Bristol-Myers Squibb | marketed | Nitrate vasodilator | Soluble guanylate cyclase (via nitric oxide) | |
| intravenous nitroglycerin | intravenous nitroglycerin | University of California, San Francisco | marketed | Nitrate vasodilator | Soluble guanylate cyclase (via nitric oxide) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Inhaled vasodilator class)
- Mallinckrodt · 1 drug in this class
- The University of Texas Health Science Center, Houston · 1 drug in this class
- University of Florida · 1 drug in this class
- Wake Forest University Health Sciences · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Inhaled Nitric Oxide (iNO) use — Competitive Intelligence Brief. https://druglandscape.com/ci/inhaled-nitric-oxide-ino-use. Accessed 2026-05-17.
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