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INH, Rifampicin, Ethambutol and Pyrazinamide — Competitive Intelligence Brief
phase 3
Anti-tuberculosis combination therapy
Multiple: mycolic acid synthesis (INH), bacterial RNA polymerase (Rifampicin), arabinosyl transferases (Ethambutol), bacterial energy metabolism (Pyrazinamide)
Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
INH, Rifampicin, Ethambutol and Pyrazinamide (INH, Rifampicin, Ethambutol and Pyrazinamide) — All India Institute of Medical Sciences. This is a fixed-dose combination of four first-line anti-tuberculosis drugs that work synergistically to inhibit bacterial cell wall synthesis and mycolic acid production, killing Mycobacterium tuberculosis.
Comparator set (1 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| INH, Rifampicin, Ethambutol and Pyrazinamide TARGET | INH, Rifampicin, Ethambutol and Pyrazinamide | All India Institute of Medical Sciences | phase 3 | Anti-tuberculosis combination therapy | Multiple: mycolic acid synthesis (INH), bacterial RNA polymerase (Rifampicin), arabinosyl transferases (Ethambutol), bacterial energy metabolism (Pyrazinamide) | |
| Moxifloxacin, Isoniazid, Rifampicin Pyrazinamide, Ethambutol | Moxifloxacin, Isoniazid, Rifampicin Pyrazinamide, Ethambutol | Tuberculosis Research Centre, India | phase 3 | Anti-tuberculosis combination therapy | Multiple: DNA gyrase (moxifloxacin), mycobacterial cell wall synthesis (isoniazid, ethambutol), RNA polymerase (rifampicin), bacterial metabolism (pyrazinamide) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Anti-tuberculosis combination therapy class)
- All India Institute of Medical Sciences · 1 drug in this class
- Tuberculosis Research Centre, India · 1 drug in this class
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Cite this brief
Drug Landscape (2026). INH, Rifampicin, Ethambutol and Pyrazinamide — Competitive Intelligence Brief. https://druglandscape.com/ci/inh-rifampicin-ethambutol-and-pyrazinamide. Accessed 2026-05-17.
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