Who are Hyruan Plus's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): vitagen plus hyruan, Hylan GF-20 alone, Hyaluronic Acid Injection, cross-linked hyaluronic acid, injection of hyaluronic acid., Synvisc-One.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

Hyruan Plus — Competitive Intelligence Brief

Hyruan Plus (Hyruan Plus) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Viscosupplement. Area: Orthopedics / Rheumatology.

phase 3 Viscosupplement Hyaluronic acid receptor (CD44) Orthopedics / Rheumatology Small molecule Live · refreshed every 30 min

Target snapshot

Hyruan Plus (Hyruan Plus) — LG Life Sciences. Hyruan Plus is a viscoelastic hyaluronic acid-based injection that provides lubrication and cushioning to damaged joints.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Hyruan Plus TARGET	Hyruan Plus	LG Life Sciences	phase 3	Viscosupplement	Hyaluronic acid receptor (CD44)
vitagen plus hyruan	vitagen plus hyruan	Taipei Medical University	marketed	Viscosupplement / Joint lubricant	Hyaluronic acid receptor (CD44); joint synovial fluid
Hylan GF-20 alone	Hylan GF-20 alone	University of Sao Paulo General Hospital	marketed	Viscosupplement	Hyaluronic acid receptor (CD44)
Hyaluronic Acid Injection	Hyaluronic Acid Injection	Wroclaw Medical University	marketed	Viscosupplement
cross-linked hyaluronic acid	cross-linked hyaluronic acid	Taipei Medical University	marketed	Viscosupplement
injection of hyaluronic acid.	injection of hyaluronic acid.	Istituto Ortopedico Rizzoli	marketed	Viscosupplement	Joint synovial fluid (viscoelastic properties)
Synvisc-One	Synvisc-One	Nature Cell Co. Ltd.	marketed	Viscosupplement; hyaluronic acid derivative	Synovial fluid; joint cartilage surfaces

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Viscosupplement class)

Istituto Ortopedico Rizzoli · 1 drug in this class
LG Life Sciences · 1 drug in this class
ProChon Biotech Ltd · 1 drug in this class
Sanofi · 1 drug in this class
Taipei Medical University · 1 drug in this class
University of Sao Paulo General Hospital · 1 drug in this class
Wroclaw Medical University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Hyruan Plus — Competitive Intelligence Brief. https://druglandscape.com/ci/hyruan-plus. Accessed 2026-05-13.

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