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High-dose anthracycline — Competitive Intelligence Brief
phase 2
anthracycline antibiotic
topoisomerase II
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
High-dose anthracycline (High-dose anthracycline) — Gruppo Italiano Malattie EMatologiche dell'Adulto. anthracyclines intercalate DNA strands, inhibiting topoisomerase II
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| High-dose anthracycline TARGET | High-dose anthracycline | Gruppo Italiano Malattie EMatologiche dell'Adulto | phase 2 | anthracycline antibiotic | topoisomerase II | |
| Idamycin Pfs | Idarubicin Hydrochloride | Pfizer Inc. | marketed | Anthracycline topoisomerase inhibitor | DNA, Topoisomerase II | 1990-01-01 |
| Idamycin Pfs | Idarubicin Hydrochloride | Pfizer Inc. | marketed | Anthracycline topoisomerase inhibitor | DNA, Topoisomerase II | 1990-01-01 |
| Idamycin Pfs | IDARUBICIN HYDROCHLORIDE | marketed | Anthracycline Topoisomerase Inhibitor | DNA, topoisomerase II | 1990-01-01 | |
| Cipro | ciprofloxacin | Bayer AG | marketed | Fluoroquinolone antibiotic | DNA topoisomerase II, DNA gyrase subunit A, DNA gyrase subunit A | 1987-10-22 |
| Amekrin | AMSACRINE | marketed | amsacrine | DNA topoisomerase 2-beta, Solute carrier family 22 member 1, DNA topoisomerase II | 1987-01-01 | |
| DOXORUBICIN HYDROCHLORIDE | DOXORUBICIN HYDROCHLORIDE | marketed | topoisomerase II | 1974-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Cipro · 11369566 · Formulation · US
- — Cipro · 9603796 · Compound · US
- — Cipro · 9205048 · Method of Use · US
- — Cipro · 9233068 · Formulation · US
- — Cipro · 8318817 · Method of Use · US
- — Cipro · 9220796 · Formulation · US
- — Cipro · 11040004 · Method of Use · US
- — Cipro · 11246863 · Formulation · US
Sponsor landscape (anthracycline antibiotic class)
- Cephalon, Inc. · 1 drug in this class
- Gruppo Italiano Malattie EMatologiche dell'Adulto · 1 drug in this class
- Sanofi · 1 drug in this class
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Cite this brief
Drug Landscape (2026). High-dose anthracycline — Competitive Intelligence Brief. https://druglandscape.com/ci/high-dose-anthracycline. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing