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Haloperidol Injection — Competitive Intelligence Brief

Haloperidol Injection (Haloperidol Injection) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: First-generation antipsychotic (typical antipsychotic). Area: Psychiatry.

marketed First-generation antipsychotic (typical antipsychotic) Dopamine D2 receptor Psychiatry Small molecule Live · refreshed every 30 min

Target snapshot

Haloperidol Injection (Haloperidol Injection) — Hennepin Healthcare Research Institute. Haloperidol blocks dopamine D2 receptors in the brain, reducing dopaminergic neurotransmission to treat psychotic symptoms and agitation.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Haloperidol Injection TARGET Haloperidol Injection Hennepin Healthcare Research Institute marketed First-generation antipsychotic (typical antipsychotic) Dopamine D2 receptor
Risperidone and Ramelteon Risperidone and Ramelteon All India Institute of Medical Sciences, Bhubaneswar marketed Atypical antipsychotic + melatonin receptor agonist combination Dopamine D2 receptor, serotonin 5-HT2A receptor, melatonin MT1/MT2 receptors
placebo with Clozapine placebo with Clozapine Shanghai Mental Health Center marketed Atypical antipsychotic Dopamine D2 receptor, Serotonin 5-HT2A receptor
Standard of Care Oral antipsychotics Standard of Care Oral antipsychotics University of Utah marketed Antipsychotic Dopamine D2 receptor; Serotonin 5-HT2A receptor
Methylphenidate, aripiprazole, and combination Methylphenidate, aripiprazole, and combination Tri-Service General Hospital marketed Stimulant and atypical antipsychotic combination Dopamine transporter (DAT), norepinephrine transporter (NET), dopamine D2 receptor (partial agonist), serotonin 5-HT1A receptor
Intramuscular olanzapine, aripiprazole Intramuscular olanzapine, aripiprazole Veterans Medical Research Foundation marketed Atypical antipsychotic Dopamine D2 receptor; serotonin 5-HT2A receptor (olanzapine); dopamine D2 partial agonist (aripiprazole)
OBR OBR Otsuka Pharmaceutical Development & Commercialization, Inc. marketed Atypical antipsychotic (depot formulation) Dopamine D2 receptor (partial agonist)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (First-generation antipsychotic (typical antipsychotic) class)

  1. Hennepin Healthcare Research Institute · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Haloperidol Injection — Competitive Intelligence Brief. https://druglandscape.com/ci/haloperidol-injection. Accessed 2026-05-13.

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