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Haloperidol Injection — Competitive Intelligence Brief
marketed
First-generation antipsychotic (typical antipsychotic)
Dopamine D2 receptor
Psychiatry
Small molecule
Live · refreshed every 30 min
Target snapshot
Haloperidol Injection (Haloperidol Injection) — Hennepin Healthcare Research Institute. Haloperidol blocks dopamine D2 receptors in the brain, reducing dopaminergic neurotransmission to treat psychotic symptoms and agitation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Haloperidol Injection TARGET | Haloperidol Injection | Hennepin Healthcare Research Institute | marketed | First-generation antipsychotic (typical antipsychotic) | Dopamine D2 receptor | |
| Risperidone and Ramelteon | Risperidone and Ramelteon | All India Institute of Medical Sciences, Bhubaneswar | marketed | Atypical antipsychotic + melatonin receptor agonist combination | Dopamine D2 receptor, serotonin 5-HT2A receptor, melatonin MT1/MT2 receptors | |
| placebo with Clozapine | placebo with Clozapine | Shanghai Mental Health Center | marketed | Atypical antipsychotic | Dopamine D2 receptor, Serotonin 5-HT2A receptor | |
| Standard of Care Oral antipsychotics | Standard of Care Oral antipsychotics | University of Utah | marketed | Antipsychotic | Dopamine D2 receptor; Serotonin 5-HT2A receptor | |
| Methylphenidate, aripiprazole, and combination | Methylphenidate, aripiprazole, and combination | Tri-Service General Hospital | marketed | Stimulant and atypical antipsychotic combination | Dopamine transporter (DAT), norepinephrine transporter (NET), dopamine D2 receptor (partial agonist), serotonin 5-HT1A receptor | |
| Intramuscular olanzapine, aripiprazole | Intramuscular olanzapine, aripiprazole | Veterans Medical Research Foundation | marketed | Atypical antipsychotic | Dopamine D2 receptor; serotonin 5-HT2A receptor (olanzapine); dopamine D2 partial agonist (aripiprazole) | |
| OBR | OBR | Otsuka Pharmaceutical Development & Commercialization, Inc. | marketed | Atypical antipsychotic (depot formulation) | Dopamine D2 receptor (partial agonist) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (First-generation antipsychotic (typical antipsychotic) class)
- Hennepin Healthcare Research Institute · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Haloperidol Injection — Competitive Intelligence Brief. https://druglandscape.com/ci/haloperidol-injection. Accessed 2026-05-13.
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