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GSK1755165; placebo; zopiclone — Competitive Intelligence Brief
phase 3
Non-benzodiazepine hypnotic (Z-drug)
GABA-A receptor
Neurology / Sleep Medicine
Small molecule
Live · refreshed every 30 min
Target snapshot
GSK1755165; placebo; zopiclone (GSK1755165; placebo; zopiclone) — GlaxoSmithKline. GSK1755165 is a selective GABA-A receptor modulator that enhances inhibitory neurotransmission to promote sleep.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| GSK1755165; placebo; zopiclone TARGET | GSK1755165; placebo; zopiclone | GlaxoSmithKline | phase 3 | Non-benzodiazepine hypnotic (Z-drug) | GABA-A receptor | |
| Zulresso | BREXANOLONE | Sage Therap | marketed | Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator | GABA-A receptor alpha-1/beta-2/gamma-2 | 2019-01-01 |
| Onfi | CLOBAZAM | Lundbeck Pharms Llc | marketed | Benzodiazepine [EPC] | GABA-A receptor alpha-1/beta-2/gamma-2 | 2011-01-01 |
| Lusedra | FOSPROPOFOL | marketed | fospropofol | GABA-A receptor | 2008-01-01 | |
| Campral | ACAMPROSATE | Allergan/AbbVie | marketed | acamprosate | GABA-A receptor alpha-1/beta-3/gamma-2 | 2004-01-01 |
| Sonata | ZALEPLON | Pfizer | marketed | gamma-Aminobutyric Acid A Receptor Agonist [EPC] | GABA-A receptor alpha-1/beta-2/gamma-2 | 1999-01-01 |
| Suprane | DESFLURANE | Baxter | marketed | General Anesthetic [EPC] | GABA-A receptor; anion channel | 1992-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Onfi · 12403090 · Formulation · US
- — Onfi · 12290597 · Formulation · US
- — Onfi · 11541002 · Formulation · US
Sponsor landscape (Non-benzodiazepine hypnotic (Z-drug) class)
- Astellas Pharma Inc · 2 drugs in this class
- EMS · 1 drug in this class
- GlaxoSmithKline · 1 drug in this class
- Henry Ford Health System · 1 drug in this class
- Sanofi · 1 drug in this class
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Cite this brief
Drug Landscape (2026). GSK1755165; placebo; zopiclone — Competitive Intelligence Brief. https://druglandscape.com/ci/gsk1755165-placebo-zopiclone. Accessed 2026-05-17.
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