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GnRH Agonist (Lupron Depot) — Competitive Intelligence Brief
phase 3
GnRH agonist
GnRH receptor
Endocrinology; Oncology; Urology
Small molecule
Live · refreshed every 30 min
Target snapshot
GnRH Agonist (Lupron Depot) (GnRH Agonist (Lupron Depot)) — Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). Lupron Depot is a GnRH agonist that suppresses luteinizing hormone and follicle-stimulating hormone, leading to decreased sex hormone production.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| GnRH Agonist (Lupron Depot) TARGET | GnRH Agonist (Lupron Depot) | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | phase 3 | GnRH agonist | GnRH receptor | |
| Lupron | leuprorelin | Accord Healthcare S.L.U. | marketed | Gonadotropin Releasing Hormone Receptor Agonist | GnRH receptors | 1985-01-01 |
| Micronor | norethisterone | Johnson & Johnson | marketed | Progestin | GnRH receptors | 1962-01-01 |
| cetrorelix (cetrotide) | cetrorelix (cetrotide) | Eugonia | marketed | GnRH antagonist | GnRH receptor | |
| Leuprolide (GnRH agonists) | Leuprolide (GnRH agonists) | University of Pisa | marketed | GnRH agonist | GnRH receptor (GNRHR) | |
| Ovulation triggering with GnRH-a+rhCG | Ovulation triggering with GnRH-a+rhCG | Fundación Santiago Dexeus Font | marketed | Gonadotropin-releasing hormone agonist combined with recombinant human chorionic gonadotropin | GnRH receptor (for GnRH-a component); LH/hCG receptor (for rhCG component) | |
| Eligard (TM) | Eligard (TM) | Chesapeake Urology Research Associates | marketed | GnRH agonist | GnRH receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (GnRH agonist class)
- Takeda · 4 drugs in this class
- Abbott · 3 drugs in this class
- Ipsen · 3 drugs in this class
- Changchun GeneScience Pharmaceutical Co., Ltd. · 3 drugs in this class
- University of Pisa · 2 drugs in this class
- Chong Qing Reproducive and Genetic Institute · 1 drug in this class
- Chesapeake Urology Research Associates · 1 drug in this class
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · 1 drug in this class
- Enteris BioPharma Inc. · 1 drug in this class
- Colorado Center for Reproductive Medicine · 1 drug in this class
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Cite this brief
Drug Landscape (2026). GnRH Agonist (Lupron Depot) — Competitive Intelligence Brief. https://druglandscape.com/ci/gnrh-agonist-lupron-depot. Accessed 2026-05-16.
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