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Columvi — Competitive Intelligence Brief
marketed
Bispecific CD20-directed CD3 T Cell Engager [EPC]
B-lymphocyte antigen CD20
Oncology
Monoclonal antibody
Live · refreshed every 30 min
Target snapshot
Columvi (glofitamab) — Roche. Columvi works by binding to the CD20 protein on B-cell lymphoma cells, triggering an immune response to destroy the cancer cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Columvi TARGET | glofitamab | Roche | marketed | Bispecific CD20-directed CD3 T Cell Engager [EPC] | B-lymphocyte antigen CD20 | 2023-01-01 |
| Lunsumio | MOSUNETUZUMAB | Roche | marketed | B-lymphocyte antigen CD20 | 2022-01-01 | |
| Ocrevus | OCRELIZUMAB | Roche | marketed | CD20-directed Cytolytic Antibody [EPC] | B-lymphocyte antigen CD20 | 2017-01-01 |
| Gazyva | obinutuzumab | Roche | marketed | CD20-directed Cytolytic Antibody [EPC] | B-lymphocyte antigen CD20 | 2013-01-01 |
| Mabthera | rituximab | Roche | marketed | CD20-directed Cytolytic Antibody [EPC] | B-lymphocyte antigen CD20 | 1997-01-01 |
| Mabthera | rituxan | Roche | marketed | CD20-directed Cytolytic Antibody | B-lymphocyte antigen CD20 | 1997-01-01 |
| EPKINLY | EPCORITAMAB-BYSP | GENMAB US, INC. | marketed | B-lymphocyte antigen CD20, T-cell surface glycoprotein CD3 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Bispecific CD20-directed CD3 T Cell Engager [EPC] class)
- · 1 drug in this class
- GENENTECH INC · 1 drug in this class
- Genmab Us, Inc. · 1 drug in this class
- Roche · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Columvi — Competitive Intelligence Brief. https://druglandscape.com/ci/glofitamab. Accessed 2026-05-13.
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