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G17DT-Irinotecan — Competitive Intelligence Brief
phase 2
Topoisomerase I inhibitor
Topoisomerase I
Oncology
Biologic
Live · refreshed every 30 min
Target snapshot
G17DT-Irinotecan (G17DT-Irinotecan) — Cancer Advances Inc.. G17DT-Irinotecan is a topoisomerase I inhibitor, which works by blocking the enzyme topoisomerase I and preventing DNA replication in cancer cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| G17DT-Irinotecan TARGET | G17DT-Irinotecan | Cancer Advances Inc. | phase 2 | Topoisomerase I inhibitor | Topoisomerase I | |
| Camptosar | irinotecan | Pfizer | marketed | Topoisomerase Inhibitor | topoisomerase I | 1996-01-01 |
| Idamycin Pfs | IDARUBICIN HYDROCHLORIDE | marketed | Anthracycline Topoisomerase Inhibitor | DNA, topoisomerase II | 1990-01-01 | |
| Idamycin Pfs | Idarubicin Hydrochloride | Pfizer Inc. | marketed | Anthracycline topoisomerase inhibitor | DNA, Topoisomerase II | 1990-01-01 |
| Idamycin Pfs | Idarubicin Hydrochloride | Pfizer Inc. | marketed | Anthracycline topoisomerase inhibitor | DNA, Topoisomerase II | 1990-01-01 |
| Cipro | ciprofloxacin | Bayer AG | marketed | Fluoroquinolone antibiotic | DNA topoisomerase II, DNA gyrase subunit A, DNA gyrase subunit A | 1987-10-22 |
| Amekrin | AMSACRINE | marketed | amsacrine | DNA topoisomerase 2-beta, Solute carrier family 22 member 1, DNA topoisomerase II | 1987-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Cipro · 11369566 · Formulation · US
- — Cipro · 9603796 · Compound · US
- — Cipro · 9205048 · Method of Use · US
- — Cipro · 9233068 · Formulation · US
- — Cipro · 8318817 · Method of Use · US
- — Cipro · 9220796 · Formulation · US
- — Cipro · 11040004 · Method of Use · US
- — Cipro · 11246863 · Formulation · US
Sponsor landscape (Topoisomerase I inhibitor class)
- Accelerated Community Oncology Research Network · 1 drug in this class
- Amgen · 1 drug in this class
- Cancer Advances Inc. · 1 drug in this class
- Chinese Academy of Medical Sciences · 1 drug in this class
- Daiichi Sankyo Co., Ltd. · 1 drug in this class
- Epidemiological and Clinical Research Information Network · 1 drug in this class
- GlaxoSmithKline · 1 drug in this class
- Seoul National University Hospital · 1 drug in this class
- St. Jude Children's Research Hospital · 1 drug in this class
- Suzhou Suncadia Biopharmaceuticals Co., Ltd. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). G17DT-Irinotecan — Competitive Intelligence Brief. https://druglandscape.com/ci/g17dt-irinotecan. Accessed 2026-05-17.
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