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Full dose of DOAC — Competitive Intelligence Brief
phase 3
Direct oral anticoagulant (DOAC)
Factor Xa or Factor IIa (thrombin)
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
Full dose of DOAC (Full dose of DOAC) — University Hospital, Brest. Direct oral anticoagulants (DOACs) inhibit specific clotting factors to prevent blood clot formation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Full dose of DOAC TARGET | Full dose of DOAC | University Hospital, Brest | phase 3 | Direct oral anticoagulant (DOAC) | Factor Xa or Factor IIa (thrombin) | |
| Pradaxa | dabigatran etexilate | Generic (originally Boehringer Ingelheim) | marketed | Direct oral anticoagulant (DOAC) — direct thrombin inhibitor | Multidrug and toxin extrusion protein 1, Multidrug and toxin extrusion protein 2, Ribosyldihydronicotinamide dehydrogenase [quinone] | 2010-10-19 |
| Rivaroxaban, Dabigatran | Rivaroxaban, Dabigatran | University Hospital, Grenoble | marketed | Direct oral anticoagulant (DOAC) | Factor Xa (rivaroxaban); Thrombin/Factor IIa (dabigatran) | |
| Rivaroxaban, dabigatran, apixaban, or edoxaban | Rivaroxaban, dabigatran, apixaban, or edoxaban | Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec | marketed | Direct oral anticoagulant (DOAC) | Factor Xa (rivaroxaban, apixaban, edoxaban) or Thrombin (dabigatran) | |
| Dabigatran; Rivaroxaban | Dabigatran; Rivaroxaban | University Hospital, Grenoble | marketed | Direct oral anticoagulant (DOAC) | Dabigatran: Factor IIa (thrombin); Rivaroxaban: Factor Xa | |
| Continuous DOAC therapy | Continuous DOAC therapy | Johns Hopkins University | phase 3 | Direct oral anticoagulant (DOAC) | Factor Xa or Factor IIa (thrombin) | |
| Dabigatran and Apixaban | Dabigatran and Apixaban | University of Sao Paulo General Hospital | phase 3 | Direct oral anticoagulant (DOAC) | Dabigatran: Factor IIa (thrombin); Apixaban: Factor Xa |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Direct oral anticoagulant (DOAC) class)
- University Hospital, Grenoble · 2 drugs in this class
- Centre Hospitalier Universitaire de Nīmes · 1 drug in this class
- Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec · 1 drug in this class
- Johns Hopkins University · 1 drug in this class
- University Hospital, Brest · 1 drug in this class
- University of Sao Paulo General Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Full dose of DOAC — Competitive Intelligence Brief. https://druglandscape.com/ci/full-dose-of-doac. Accessed 2026-05-16.
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