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Fosfomycin and imipenem — Competitive Intelligence Brief
marketed
Beta-lactam antibiotic combination
Bacterial cell wall synthesis (MurA enzyme and penicillin-binding proteins)
Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
Fosfomycin and imipenem (Fosfomycin and imipenem) — Juan A. Arnaiz. Fosfomycin and imipenem together provide dual antibiotic action by inhibiting bacterial cell wall synthesis through different mechanisms to treat serious infections.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Fosfomycin and imipenem TARGET | Fosfomycin and imipenem | Juan A. Arnaiz | marketed | Beta-lactam antibiotic combination | Bacterial cell wall synthesis (MurA enzyme and penicillin-binding proteins) | |
| Ilaprazole + Amoxicillin | Ilaprazole + Amoxicillin | Il-Yang Pharm. Co., Ltd. | marketed | Proton pump inhibitor + Beta-lactam antibiotic combination | H+/K+-ATPase (ilaprazole); Bacterial cell wall peptidoglycan (amoxicillin) | |
| Vonoprazan+amoxicillin 7 days | Vonoprazan+amoxicillin 7 days | Xijing Hospital of Digestive Diseases | marketed | Potassium-competitive acid blocker + beta-lactam antibiotic combination | H+/K+-ATPase (vonoprazan); bacterial cell wall peptidoglycan (amoxicillin) | |
| Rabeprazole, Amoxicillin | Rabeprazole, Amoxicillin | Mackay Memorial Hospital | marketed | Proton pump inhibitor + Beta-lactam antibiotic combination | H+/K+-ATPase (rabeprazole); Bacterial penicillin-binding proteins (amoxicillin) | |
| Ceftolozane-tazobactam + Meropenem | Ceftolozane-tazobactam + Meropenem | National University of Singapore | marketed | Beta-lactam antibiotic combination | Bacterial penicillin-binding proteins (PBPs); beta-lactamase inhibition | |
| ceftriaxone/oxacillin | ceftriaxone/oxacillin | UPECLIN HC FM Botucatu Unesp | marketed | Beta-lactam antibiotic combination | Penicillin-binding proteins (PBPs) | |
| Azithromycin and amoxicillin | Azithromycin and amoxicillin | University of Alabama at Birmingham | marketed | Macrolide and beta-lactam antibiotic combination | Bacterial 50S ribosomal subunit (azithromycin); bacterial cell wall peptidoglycan (amoxicillin) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Beta-lactam antibiotic combination class)
- Juan A. Arnaiz · 1 drug in this class
- National University of Singapore · 1 drug in this class
- Population Health Research Institute · 1 drug in this class
- Radboud University Medical Center · 1 drug in this class
- UPECLIN HC FM Botucatu Unesp · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Fosfomycin and imipenem — Competitive Intelligence Brief. https://druglandscape.com/ci/fosfomycin-and-imipenem. Accessed 2026-05-16.
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